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Table 6 Risk factors for mortality in patients admitted to intensive care with haematological malignancy

From: Admission factors associated with hospital mortality in patients with haematological malignancy admitted to UK adult, general critical care units: a secondary analysis of the ICNARC Case Mix Programme Database

Study

Factors identified that are associated with hospital mortality

Owzcuk and colleagues [16]

High SAPS II, SOFA score or APACHE II score, neutropaenia, hypotension, cardiovascular failure

Yau and colleagues [9]

Progression of underlying malignancy

Massion and colleagues [11]

Respiratory failure, fungal infection, number of organ failures, haemopoeitic stem cell transplant status

Benoit and colleagues [32]

Leukopaenia, use of vasopressors, urea >0.75 g/l

Gordon and colleagues [6]

Hepatic failure, central nervous system failure, SAPS II score >66

Lim and colleagues [39]

Raised bilirubin, inotropic support, more than three organ failures

Lloyd-Thomas and colleagues [8]

High APACHE II score, number of organ failures, mechanical ventilation

Brunet and colleagues [10]

SAPS II score, more than one organ failure

Kroschinsky and colleagues [14]

Haemofiltration, high SAPS II score

Silfvast and colleagues [50]

Maximal SOFA score on admission

Cornet and colleagues [17]

SAPS II and SOFA score over 96 hours

Lamia and colleagues [12]

Severe sepsis or septic shock, vasopressor use, invasive ventilation, neutropaenia, allogeneic haemopoeitic stem cell transplant, high SAPS II, SOFA score, ODIN score or LODS score

Bianchi and colleagues [41]

Mechanical ventilation, neutropaenia, renal failure

  1. APACHE II: Acute Physiology and Chronic Health Evaluation II; LODS: Logistic Organ Dysfunction Score; ODIN: Organ Dysfunction and/or Infection score; SAPS II: Simplified Acute Physiology Score II; SOFA: Sequential Organ Failure Assessment.