Microcirculatory changes and skeletal muscle oxygenation measured at rest by non-infrared spectroscopy in patients with and without diabetes undergoing haemodialysis

Table 2 Data corrected for possible variations in total haemoglobin concentration related to dialysis-induced fluid removal

	Patients without diabetes (n = 10)				Patients with diabetes (n = 10)
Variable	T0	T1	T2	T3	T0	T1	T2	T3
Total haemoglobin concentration (μM/l)	46.62^a ± 18.44	56.33 ± 17.05	56.44 ± 17.38	56.25 ± 17.69	45.17^a ± 17.43	58.33 ± 21.40	59.61 ± 22.75	66.53 ± 23.51
Tissue oxygen content (ml O₂/100 ml)	0.18 ± 0.10	0.23 ± 0.09	0.20 ± 0.13	0.21 ± 0.12	0.20^a ± 0.10	0.24 ± 0.13	0.26^c ± 0.14	0.32 ± 0.20
Microvascular compliance (μM/mmHg)	0.153^a ± 0.109	0.049^b ± 0.035	0.010 ± 0.007	0.004 ± 0.001	0.203^a ± 0.150	0.039 ± 0.058	0.016 ± 0.017	0.013 ± 0.010

To take into account possible total haemoglobin concentration variations related to dialysis-induced fluid removal, the near-infrared spectroscopy total haemoglobin concentration values and related variables (tissue oxygen content, and compliance) were corrected for vascular haemoglobin changes during dialysis. T0, predialysis. The statistical analysis was performed with the Wilcoxon test, considering P < 0.05 significant: ^a P < 0.05 vs. beginning of the second hour (T1), beginning of the third hour (T2), beginning of the fourth hour (T3); ^b P < 0.05 vs. T2, T3; ^cP < 0.05 vs. T3.

ISSN: 1364-8535