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Table 4 Regional hemodynamics

From: Continuous terlipressin versus vasopressin infusion in septic shock (TERLIVAP): a randomized, controlled pilot study

 

Baseline

12 hours

24 hours

36 hours

48 hours

CBI

(mL/min/m)

     

TP

353 ± 226

387 ± 202

367 ± 179

299 ± 139

351 ± 129

AVP

397 ± 171

409 ± 209

367 ± 222

308 ± 185*

305 ± 201*

NE

327 ± 135

358 ± 173

312 ± 145

271 ± 136

252 ± 206

PDR

(%)

     

TP

13 ± 6

14 ± 5

13 ± 4

12 ± 5

13 ± 4

AVP

15 ± 5

15 ± 6

13 ± 7

12 ± 7*

11 ± 6*

NE

14 ± 5

13 ± 5

12 ± 6

11 ± 6*

10 ± 7*

P g-a CO 2

(mmHg)

     

TP

23 ± 11

24 ± 8

22 ± 6

20 ± 6

20 ± 7

AVP

25 ± 7

28 ± 8

27 ± 9

28 ± 12

28 ± 10

NE

24 ± 11

28 ± 10

28 ± 8

26 ± 8

31 ± 12

Urinary output

(mL/h)

     

TP

34.6 ± 31.3

69.3 ± 70.4

49.2 ± 49.5

48.5 ± 41.4

46.6 ± 33.3

AVP

42.3 ± 46.9

42 ± 39

42 ± 41.6

40.7 ± 45.7

43.3 ± 58.7

NE

38.6 ± 34.3

55.4 ± 74.1

66 ± 77

58.6 ± 56.1

58.6 ± 63.8

  1. AVP = arginine vasopressin; CBI = blood clearance of indocyanine green; NE = norepinephrine; PDR = plasma disappearance rate of indocyanine green; Pg-aCO2 = gastric-mucosal arterial carbon dioxide partial pressure difference; TP = terlipressin.
  2. * P < 0.05 vs. baseline (significant time effect); P < 0.05 vs. TP (significant group effect); P < 0.05 vs. AVP (significant group effect); § P < 0.05 vs. NE (significant group effect).