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Figure 1 | Critical Care

Figure 1

From: Pharmacokinetics of epinephrine in patients with septic shock: modelization and interaction with endogenous neurohormonal status

Figure 1

Goodness-of-fit plot for the final model, observed vs. model-predicted epinephrine plateau concentrations. The prediction of the epinephrine plateau concentration at steady state infusion rate is: Cplateau (nmol/L) = (rate of infusion + R0)/(127 × (BW/70)0.60 × (SAPS II/50)-0.67) where R0 (nmol/hr) is the baseline rate of epinephrine infusion rate, BW (kg) is the body weight, and SAPS II is the severity score (new simplified acute physiology score) at intensive care admission.

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Critical Care

ISSN: 1364-8535