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Table 1 PROGRESS demographics

From: The international PROGRESS registry of patients with severe sepsis: drotrecogin alfa (activated) use and patient outcomes

Variable

DrotAA

n = 882

Non-DrotAA

n = 11,610

Total

n = 12,492

P value

Gender (male), n (%)

511 (57.9)

6903 (59.5)

7414 (59.3)

0.38

Age, years

57.6 (± 16.8)

60.6 (± 17.5)

60.3 (± 17.5)

<0.001

Ethnicity, n (%):

(n = 777)

(n = 10,247)

(n = 11,204)

<0.001

   Caucasian

479 (61.6)

4933 (47.3)

5412 (48.3)

 

   Hispanic

127 (16.3)

2353 (22.6)

2480 (22.1)

 

   East/South East Asia

55 (7.1)

2091 (20.1)

2146 (19.2)

 

   Other

48 (6.2)

283 (2.7)

331 (3.0)

 

   African descent

40 (5.1)

194 (1.9)

234 (2.1)

 

   Western Asia

28 (3.6)

573 (5.5)

601 (5.4)

 

Region, n (%):

(n = 882)

(n = 11,610)

(n = 12,492)

<0.001

   US/Canada

307 (34.8)

1666 (14.3)

1973 (15.8)

 

   European Union

187 (21.2)

2492 (21.5)

2679 (21.4)

 

   Other

388 (44.0)

7452 (64.2)

7840 (62.8)

 

Referral pattern, n (%):

(n = 876)

(n = 11,535)

(n = 12,410)

<0.001

   ICU transfer from ER

238 (27.2)

2522 (21.9)

2760 (22.2)

 

   ICU transfer from ward

206 (23.5)

3214 (27.9)

3420 (27.6)

 

   ICU transfer from OR

156 (17.8)

2408 (20.9)

2564 (20.7)

 

   ICU transfer from other hospital

143 (16.3)

1515 (13.1)

1658 (13.4)

 

   ICU transfer from other ICU

47 (5.4)

338 (2.9)

385 (3.1)

 

   Direct to ICU from community

40 (4.6)

790 (6.8)

830 (6.7)

 

   Direct to ICU from intermediate care

40 (4.6)

654 (5.7)

694 (5.6)

 

   ICU transfer from another chronic care facility

4 (0.5)

51 (0.4)

55 (0.4)

 

   Other/unknown

2 (0.2)

42 (0.4)

44 (0.4)

 
  1. DrotAA = drotrecogin alfa (activated); ER = emergency room; ICU = intensive care unit; OR = operating room; PROGRESS = Promoting Global Research Excellence in Severe Sepsis.