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Table 3 Ventilatory pattern and respiratory mechanics at the end of the study

From: Determinants of weaning success in patients with prolonged mechanical ventilation

 

Successful weaning group

(n = 16)

Failed weaning group

(n = 14)

P value

Ventilatory pattern

   

   VT, mL

385.8 ± 132.2

289.3 ± 138.4

NS

   f, breaths/min

22.6 ± 6.0

27.4 ± 7.3

NS

   f/VT

74.1 ± 44.0

148.2 ± 121.4

0.03

Respiratory mechanics

   

   CLdyn, L/cm H2O

0.067 ± 0.033

0.049 ± 0.024

NS

   RL, cm H2O/L per s

8.8 ± 5.8

14.4 ± 14.2

NS

   PEEPi,dyn, cm H2O

1.5 ± 1.0

1.7 ± 1.66

NS

Inspiratory muscle function

   

   MIP, cm H2O

57.3 ± 18.2

38.6 ± 13.5

0.001

   Pdimax, cm H2O

43.0 ± 20.0

27.7 ± 12.5

0.01

   Pdisw/Pdimax, percentage

23.1 ± 7.9

42.5 ± 22.9

0.003

   PTPdi/min, cm H2O/s

194.1 ± 84.8

216.2 ± 136.8

NS

   TTdi

0.08 ± 0.029

0.14 ± 0.054

0.009

  1. CLdyn, dynamic lung compliance; f, spontaneous breathing frequency; MIP, maximum inspiratory pressure; NS, not significant; Pdimax, maximum transdiaphragmatic pressure; Pdisw, tidal diaphragmatic pressure; PEEPi,dyn, dynamic intrinsic positive end-expiratory pressure; PTPdi/min, pressure time product of the diaphragm per minute; RL, pulmonary resistance; TTdi, tension-time index of diaphragm; VT, tidal volume.