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Table 3 Changes in arterial lactate, hemoglobin, blood gases and oxygen saturations as mean arterial pressure was increased from 65 mmHg to 85 mmHg with norepinephrine

From: Increasing arterial blood pressure with norepinephrine does not improve microcirculatory blood flow: a prospective study

  Mean arterial blood pressure ANOVA Linear trend
  65 mmHg 75 mmHg 85 mmHg P P
Arterial lactate (mmol/L) 2.6 ± 2.8 2.4 ± 2.7 2.5 ± 2.7 0.27 0.32
Hemoglobin (g%) 9.6 ± 2.3 9.6 ± 2.4 9.6 ± 2.3 0.76 0.79
Arterial pH 7.26 ± 0.11 7.26 ± 0.11 7.26 ± 0.11 0.44 0.29
Arterial PCO 2 (mmHg) 39 ± 10 39 ± 10 40 ± 11 0.73 0.57
Arterial PO 2 (mmHg) 112 ± 48 113 ± 45 108 ± 34 0.39 0.25
Arterial HCO 3 - (mmol/l) 18 ± 5 18 ± 5 18 ± 5 0.50 0.43
Arterial oxygen saturation 0.96 ± 0.02 0.96 ± 0.02 0.96 ± 0.03 0.67 0.44
Mixed venous pH 7.23 ± 0.11 7.24 ± 0.10 7.24 ± 0.10 0.78 0.49
Mixed venous PCO 2 (mmHg) 45 ± 11 45 ± 11 45 ± 11 0.90 0.69
Mixed venous PO 2 (mmHg) 42 ± 7 43 ± 7 44 ± 8* 0.04 0.02
Mixed venous HCO 3 - (mmol/l) 19 ± 5 19 ± 5 19 ± 5 0.18 0.08
Mixed venous oxygen saturation 0.70 ± 0.08 0.72 ± 0.08* 0.73 ± 0.07* 0.01 0.005
Central venous oxygen saturation 0.74 ± 0.08 0.76 ± 0.08* 0.77 ± 0.08* 0.01 0.004
Arterial anion gap (mmol/L) 18 ± 6 19 ± 6 20 ± 7 0.16 0.06
  1. * P < 0.05 vs. basal (Dunnett post hoc test after repeated measures ANOVA).
  2. ANOVA = analysis of variance; HCO3 = bicarbonate; pCO2 = partial pressure of carbon dioxide; pO2 = partial pressure of oxygen.