Table 1 Summary of clinical characteristics and outcomes stratified by hypoglycemia and blood glucose variability
From: The impact of early hypoglycemia and blood glucose variability on outcome in critical illness
Characteristic/outcome | Total (n = 66,184) | Hypoglycemic episode only (n = 7209) | Blood glucose variability (n = 1913) | Neither (n = 57,969) | P value |
|---|---|---|---|---|---|
Age (mean [SD]) (years) | 61.1 (18) | 59.2 (20) | 62.6 (17) | 61.4 (18) | <0.001 |
Male sex (%) | 59.0 | 53.4 | 53.2 | 59.8 | <0.001 |
Co-morbid disease (%) | 24.2 | 25.7 | 29.8 | 23.8 | <0.001 |
   Cardiovascular | 10.7 | 10.4 | 15.5 | 10.6 | 0.016 |
   Respiratory | 7.8 | 7.7 | 9.2 | 7.8 | 0.08 |
   Immunocompromised | 5.1 | 6.2 | 6.2 | 4.9 | <0.001 |
   End-stage kidney disease | 3.6 | 6.6 | 7.4 | 3.1 | <0.001 |
   Metastatic cancer | 2.8 | 2.7 | 1.8 | 2.8 | 0.03 |
   Liver disease | 2.5 | 4.2 | 3.1 | 2.3 | <0.001 |
   Hematologic malignancy | 1.5 | 1.7 | 1.4 | 1.5 | 0.41 |
Non-elective admission (%) | 65.9 | 76.9 | 79.8 | 64.1 | <0.001 |
Surgical admission (%) | 45.7 | 34.4 | 27.7 | 47.6 | <0.001 |
   Cardiovascular (%) | 33.8 | 30.4 | 37.3 | 34.1 | <0.001 |
   Trauma (%) | 9.3 | 7.4 | 4.3 | 9.7 | <0.001 |
Primary diagnosis (%) | Â | Â | Â | Â | Â |
   Sepsis/septic shock | 23.0 | 30.4 | 26.6 | 21.9 | <0.001 |
   Respiratory | 13.4 | 10.0 | 13.9 | 13.8 | <0.001 |
   Gastrointestinal (other) | 10.5 | 10.4 | 8.1 | 10.6 | 0.025 |
   Cardiac | 10.2 | 9.1 | 19.5 | 10.0 | <0.001 |
   Neurologic | 9.8 | 7.3 | 6.3 | 10.2 | <0.001 |
   Hepatic | 6.3 | 7.6 | 5.2 | 6.2 | <0.001 |
   Metabolic/poisoning | 6.8 | 11.6 | 11.2 | 6.1 | <0.001 |
   Gastrointestinal Bleeding | 3.2 | 2.8 | 3.0 | 3.2 | 0.09 |