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Table 1 Summary of clinical characteristics and outcomes stratified by hypoglycemia and blood glucose variability

From: The impact of early hypoglycemia and blood glucose variability on outcome in critical illness

Characteristic/outcome Total
(n = 66,184)
Hypoglycemic episode only
(n = 7209)
Blood glucose variability
(n = 1913)
Neither
(n = 57,969)
P value
Age (mean [SD]) (years) 61.1 (18) 59.2 (20) 62.6 (17) 61.4 (18) <0.001
Male sex (%) 59.0 53.4 53.2 59.8 <0.001
Co-morbid disease (%) 24.2 25.7 29.8 23.8 <0.001
   Cardiovascular 10.7 10.4 15.5 10.6 0.016
   Respiratory 7.8 7.7 9.2 7.8 0.08
   Immunocompromised 5.1 6.2 6.2 4.9 <0.001
   End-stage kidney disease 3.6 6.6 7.4 3.1 <0.001
   Metastatic cancer 2.8 2.7 1.8 2.8 0.03
   Liver disease 2.5 4.2 3.1 2.3 <0.001
   Hematologic malignancy 1.5 1.7 1.4 1.5 0.41
Non-elective admission (%) 65.9 76.9 79.8 64.1 <0.001
Surgical admission (%) 45.7 34.4 27.7 47.6 <0.001
   Cardiovascular (%) 33.8 30.4 37.3 34.1 <0.001
   Trauma (%) 9.3 7.4 4.3 9.7 <0.001
Primary diagnosis (%)      
   Sepsis/septic shock 23.0 30.4 26.6 21.9 <0.001
   Respiratory 13.4 10.0 13.9 13.8 <0.001
   Gastrointestinal (other) 10.5 10.4 8.1 10.6 0.025
   Cardiac 10.2 9.1 19.5 10.0 <0.001
   Neurologic 9.8 7.3 6.3 10.2 <0.001
   Hepatic 6.3 7.6 5.2 6.2 <0.001
   Metabolic/poisoning 6.8 11.6 11.2 6.1 <0.001
   Gastrointestinal Bleeding 3.2 2.8 3.0 3.2 0.09
  1. SD = standard deviation.