Individual time courses. (a to d) Results for cytokine de novo synthesis capacities and (d) the accumulated multiple organ dysfunction syndrome (MODS) score are depicted for each patient on admission, 24 hours, and 72 hours after trauma, respectively. Results are calculated as percentage of cytokine positive CD14+ monocytes. All patients showed a significant amelioration of organ function 72 hours after admission to the ICU. Data are given as boxplots (median, 5th, 95th percentile). n = 13 patients.