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Table 5 Factors related to acute illness

From: Risk factors for delirium in intensive care patients: a prospective cohort study

  n mean (SD) or % univariate multivariate
  D ND D ND P* OR (CI) OR (CI)
   length of stay in the ICU before inclusion* 155 368 7.9 (11.5) 1.7 (2.3) <0.001 1.26 (1.17 to 1.35)  
   length of stay in the ICU before inclusion >1 day* 87/155 116/368 56% 32% <0.001 2.78 (1.89 to 4.09)  
length of stay in the ICU before inclusion >2 days* 70/155 46/368 45% 13% <0.001 5.77 (3.71 to 8.97)  
admission for internal medicine 91/155 175/368 48% 59% 0.013 1.57 (1.07 to 2.29) 4.01 (1.46 to 11.01)
high risk of mortality (SAPS >40; APACHE >24) 29/73 29/139 40% 21% 0.003 2.50 (1.31 to 4.66)  
   APACHE II 33 87 19.7 (7.3) 18.6 (7.5) 0.47 1.02 (0.97 to 1.08)  
   SAPS II 54 54 33.4 (12.6) 28.6 (10.7) 0.04 1.04 (1.01 to 1.08)  
highest TISS 28 score 88 191 34.9 (5.7) 31.9 (6.6) <0.001 1.08 (1.04 to 1.13)  
mean TISS 28 88 191 30.8 (3.9) 29.1 (5.6) 0.004 1.07 (1.02 to 1.13)  
TISS 28 cut off 30 (318 minutes) 68/88 104/191 77% 55% <0.001 2.81 (1.60 to 5.05)  
psychoactive medication 103/135 146/289 76% 51% <0.001 3.15 (1.99 to 4.99) 3.34 (1.50 to 11.23)
   benzodiazepine 18/68 24/215 27% 11% 0.003 2.89 (1.44 to 5.69)  
   Morphine 24/70 54/217 34% 25% 0.09 1.58 (0.88 to 2.82)  
   sedation 65/88 24/140 74% 17% <0.001 13.66 (7.15 to 26.10)  
endotracheal tube or tracheastomy 27/118 11/272 23% 4% <0.001 7.04 (3.36 to 14.76) 8.07 (1.18 to 55.06)
gastric tube 44/120 19/275 37% 7% <0.001 7.80 (4.30 to 14.16)  
bladder catheter 115/120 227/280 96% 81% <0.001 5.37 (2.09 to 13.80)  
arterial catheter 108/120 231/278 90% 83% 0.05 1.83 (0.93 to 3.59)  
number of perfusions 120 280 4.2 (2.0) 3.1 (1.7) <0.001 1.35 (1.20 to 1.52)  
more than three perfusions 65/120 81/278 54% 29% <0.001 2.87 (1.85 to 4.47) 2.74 (1.07 to 7.05)
number of vascular catheters 120 280 1.2 (0.5) 1.3 (0.6) 0.18 0.74 (0.47 to 1.17)  
no normal food 92/120 127/275 77% 46% <0.001 3.83 (2.36 to 6.22)  
fever 10/119 16/278 8% 6% 0.222 1.50 (0.66 to 3.42)  
  1. *: the only reason for later inclusion of patients was a score on the Glasgow Coma Scale below 10.
  2. Continuous variables are presented in number, mean and standard deviation (SD); categorical variables are presented in number per group and percentage.
  3. * P value of difference in groups, calculated with independent samples t-test for continuous variables, with Chi squared for categorical variables.
  4. APACHE = Acute Physiology And Chronic Health Evaluation; CI = confidence interval; D = delirium group; ICU = intensive care unit; ND = non-delirium group; OR = odds ratio; SAPS = Simplified Acute Physiology Score; TISS 28 = The Therapeutic Intervention Scoring System-28.