Figure 1

TREM-1 expression was higher in patients with AP, but this increase was not associated with mortality, or with the presence of infection. (a) Triggering receptor expressed on myeloid cells-1 (TREM-1) expression was measured on blood monocytes from patients with mild acute pancreatitis (AP; n = 18), patients with severe AP (n = 11), and healthy volunteers (n = 50). Samples were taken from patients on admission (day 0) and one and three days later. One patient with mild AP was discharged from the hospital before the third blood sample was taken, and one patient with severe AP died after the first blood sample was collected. (b) Patients with AP were grouped according to survival (24 of these patients survived and 5 died). (c) Patients with AP were grouped according to the presence of infection (5 of the 29 patients developed infection). (d) Soluble TREM-1 expression was measured in the serum of patients with AP, which were grouped according to survival. * P < 0.05, ** P < 0.01, *** P < 0.001; the signs over each bar represent comparisons vs. healthy volunteers (H). MFI = mean fluorescence intensity.