Figure 2
From: Time course of angiopoietin-2 release during experimental human endotoxemia and sepsis
Correlation of Ang-2 with TNF-α, E-selectin and heart rate/mean arterial pressure index after LPS challenge in healthy subjects. Dot blots showing the correlation between circulating angiopoietin (Ang)-2 and (a) plasma levels of TNF-alpha, (b) plasma levels of the soluble endothelial specific adhesion molecule E-selectin, and (c) the heart rate/mean arterial pressure index (HR/MAP index) at 6.5 hours after lipopolysaccharide (LPS) challenge in 21 subjects (placebo (n = 6), and medication groups: 350 mg (n = 5). 700 mg (n = 6), and 1400 mg (n = 4), respectively). Pearsons correlation coefficient was used after logarithmic transformation of variables (axes denote percentage increase after logarithmic transformation; baseline = 100%).