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Table 1 Clinical characteristics of ICU patients receiving RRT

From: Delivered dose of renal replacement therapy and mortality in critically ill patients with acute kidney injury

 

All

CRRT

IRRT

Mixed RRT

P CRRT vs IRRT

P (three groups)

n (%)

471

338 (72)

87 (18)

46 (10)

  

Male sex (%)

67.7

66.6

70.1

71.7

0.529

0.679

Age (years)

63.6 ± 16.2

62.1 ± 16.9

68.3 ± 13

65.8 ± 14.7

0.004

0.009

Body weight (kg)

79.3 ± 19.3

79.4 ± 19.7

77.9 ± 19.6

81.4 ± 15

0.269

0.229

ICU admission

      

   SAPS II

50 ± 18

50 ± 17

50 ± 19

51 ± 21

0.508

0.788

   SOFA

10 ± 4

10 ± 3

10 ± 3

11 ± 4

0.703

0.012

   Creatinine (μmol/L)

99(80 to 150)

100 (80 to 150)

106 (80 to 177)

97 (80 to 115)

0.277

0.278

   Chronic kidney disease (%)

56.3

55.9

55.2

60.9

0.901

0.796

Diagnosis

      

   Sepsis (%)

32.7

38.8

14.9

21.7

< 0.001

< 0.001

   Post-surgical (%)

29.7

21.9

51.7

45.7

< 0.001

< 0.001

Admission department

      

   Emergency (%)

30.4

33.4

19.5

28.3

0.012

0.040

   Medicine (%)

21.0

24.0

12.6

15.2

0.022

0.041

   Surgery (%)

48.6

42.6

67.8

56.5

< 0.001

< 0.001

   Hospital to ICU admission (days)

1 (0 to 5)

1 (0 to 4)

2 (0 to 7)

1 (0 to 5)

0.042

0.146

RRT

      

   ICU admission to start RRT (days)

3 (1 to 7)

2 (1 to 7)

3.5 (1 to 8.5)

3 (2 to 5)

0.884

0.700

   RIFLE class at RRT initiation

      

Risk (%)

11.3

12.7

5.8

10.9

0.067

0.186

Injury (%)

28.5

27.5

31.0

30.4

0.515

0.746

Failure (%)

57.3

56.8

60.9

54.3

0.489

0.759

Non-renal indication (%)

2.8

3.0

2.3

2.2

0.740

0.920

   SOFA at RRT initiation

11 ± 3

12 ± 3

10 ± 2

13 ± 3

< 0.001

< 0.001

   Creatinine at RRT initiation (μmol/L)

265 (177 to 368)

274 (177 to 380)

243 (203 to 301)

194 (141 to 309)

0.319

0.031

   Start to end RRT (days)

3 (2 to 7)

3 (2 to 6)

4 (2 to 7)

13.5 (7 to 26.5)

0.113

< 0.001

Indication for RRT initiation

      

   Azotaemia

72.1

67.9

86.2

76.1

0.001

0.003

   RIFLE class

64.4

64.9

60.9

67.4

0.495

0.715

   Fluid overload

58.6

61.6

51.7

50.0

0.096

0.116

   Oliguria

43.6

48.1

28.7

39.1

0.001

0.004

Outcome

      

   ICU mortality (%)

47.6

54.1

22.1

44.7

< 0.001

< 0.001

   Mechanical ventilation (days)

10 (3 to 19)

10 (4 to 19)

8 (1 to 17)

16 (11 to 38)

0.037

0.002

   ICU length of stay (days)

14 (7 to 27)

13 (6.5 to 26)

14 (6 to 23)

25 (15 to 42)

0.769

< 0.001

  1. CRRT = continuous renal replacement therapy; ICU = intensive care unit; IRRT = intermittent renal replacement therapy; RIFLE = Risk-Injury-Failure-Loss-Endstage renal disease; RRT = renal replacement therapy; SAPS II = simplified acute physiology score; SOFA = sequential organ failure assessment.
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Critical Care

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