Figure 4

Relative changes in intestinal microcirculation and tissue oxygen tension (ptiO₂). Black squares indicate relative changes in microcirculatory blood flow (MBF) in the goal-directed colloid fluid therapy (GD-C) group. Open squares indicate relative changes in ptiO₂ in the GD-C group. Black triangles indicate relative changes in MBF in the goal-directed Ringer lactate fluid therapy (GD-RL) group. Open triangles indicate relative changes in ptiO₂ in the GD-RL group. Black circles indicate relative changes in MBF in the restricted Ringer lactate fluid therapy (R-RL) group. Open circles indicate relative changes in ptiO₂ in the R-RL group. The R-RL group received 3 mL/kg per hour of lactated Ringer solution throughout the entire experiment. The GD-RL group received 3 mL/kg per hour of lactated Ringer solution plus 250 mL of lactated Ringer solution if mixed venous oxygen saturation (SvO₂) was less than 60%. The GD-C group received 3 mL/kg per hour of lactated Ringer solution plus 250 mL of hydroxyethyl starch (130/0.4) if SvO₂ was less than 60%. Baseline was set at 100% for all parameters. Significant differences (P < 0.05) for area under the curve: ^†R-RL versus GD-C, ^$GD-RL versus GD-C. Significant differences (P < 0.05) for analysis of variance for repeated measurements (Tukey post hoc test): ^≠R-RL versus GD-C, ^§GD-RL versus GD-C.