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Table 5 Procalcitonin changes at various time points in patients with bacterial sepsis according to the outcome

From: Procalcitonin kinetics within the first days of sepsis: relationship with the appropriateness of antibiotic therapy and the outcome

 

Survivors

Nonsurvivors

P value

PCT at D1 (n = 180; 129 S, 51 NS)a

21.7 (52.0)

43.0 (107.4)

0.30

PCT at D2 (n = 163; 117 S, 46 NS)a

25.7 (41.5)

43.9 (76.3)

0.13

ΔPCT D1–D2

+1.8 (35.9)

+4.8 (44.6)

0.44

PCT at D3 (n = 164; 117 S, 47 NS)a

21.3 (41.0)

40.8 (85.7)

0.04

ΔPCT D2–D3

-4.5 (24.0)

+5.4 (52.3)

<0.01

PCT at D4 (n = 121; 80 S, 41 NS)a

14.0 (29.1)

34.9 (66.6)

<0.01

ΔPCT D1–D4

-3.2 (38.8)

-14.1 (97.8)

0.05

ΔPCT D3–D4

-5.9 (14.8)

-13.1 (28.2)

0.06

  1. S, survivors; NS, nonsurvivors; PCT, procalcitonin; D1, day sepsis is diagnosed; ΔPCT D1–D2, procalcitonin decrease between day 2 and day 1 after the onset of sepsis, and so forth. aMissing data are due to insufficient serum samples or death of patients within the 1-day, 2-day or 3-day period following the onset of sepsis.
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Critical Care

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