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Table 3 Cell counts in lung lavage fluid and histopathological examination of lung tissue of C57Bl/6 mice.

From: Mechanical ventilation using non-injurious ventilation settings causes lung injury in the absence of pre-existing lung injury in healthy mice

 

Control

LVT

HVT

Total cells (× 104/ml BALF)

44 (30 to 45)

23 (14 to 221)

14 (10 to 20)

Neutrophils (× 104/ml BALF)

0.13 (0.0 to 0.73)

1.9 (1.2 to 2.8)

4.5 (3.9 to 12.7)*

VILI–score

0.0 (0.0 to 0.5)

1.0 (0.0 to 3.0)

2.0 (1.0 to 4.5)*

  1. Data are presented as median (IQR). Control = spontaneously breathing mice, LVT = low tidal volumes, HVT = high tidal volumes, BALF = broncho-alveolar lavage fluid, VILI = ventilator-induced lung injury. n = 6 per group. *p < 0.05 vs. control.
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Critical Care

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