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Figure 1 | Critical Care

Figure 1

From: Phosphodiesterase 4 inhibition but not beta-adrenergic stimulation suppresses tumor necrosis factor-alpha release in peripheral blood mononuclear cells in septic shock

Figure 1

Modulation of Toll-like-receptor 4 (TLR4) surface expression on CD14+ monocytes of healthy volunteers (n = 20). Responses to (a) increasing concentrations of lipopolysaccharide (LPS), (b) time dependency under continuous LPS stimulation (100 ng/mL), and (c) increasing concentrations of isoprenaline are shown. TLR4 expression was measured by flow cytometry, and histograms of median fluorescence intensity (MFI) and averages with standard error of the mean from all probands are shown. FITC, fluorescein isothiocyanate.

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Critical Care

ISSN: 1364-8535