Group | Subgroup | Control | Insulin | p Value |
---|---|---|---|---|
Study interval | Â | August to December 2004 | June 2005 to June 2006 | Â |
Procedure, n (%): | CABG | 97 (31.8) | 218 (29.3) | 0.41 |
 | Valve | 132 (43.3) | 291 (39.0) | 0.21 |
 | Combined | 76 (24.9) | 236 (31.7) | 0.03 |
 | Redo | 43 (14.2) | 104 (13.9) | 1.0 |
 | Emergency | 33 (10.9) | 61 (8.2) | 0.19 |
ICU length of stay (days), median (min-max) | Â | 2 (1 to 73) | 2 (1 to 106) | 0.61 |
Aprotinin usage, n (%) | Â | 29 (9.5) | 103 (13.8) | 0.06 |
Administration of intravenous diuretics into the ICU, n(%) | Â | 50 (16.4) | 121 (16.2) | 1.0 |
Patients with packed cell transfusion, n (%) | Â | 240 (78.7) | 524 (70.3) | 0.006 |
Packed cells per patient, median (min-max) | Â | 2 (0 to 18) | 2 (0 to 19) | 0.66 |
Blood glucose level (mg/dL): | Induction | 109 ± 39 | 104 ± 24 | 0.20 |
 | End of surgery | 115 ± 25 | 108 ± 22 | < 0.001 |
 | Admission to ICU | 118 ± 29 | 107 ± 22 | < 0.001 |
 | Mean in the ICU | 133 ± 29 | 103 ± 15 | < 0.0001 |
Serum creatinine levels (g/dL): | Â | Â | Â | Â |
   Non-diabetics | Preoperative | 1.0 ± 0.7 | 1.0 ± 0.5 | 0.99 |
 | Max in the ICU | 1.3 ± 1.0 | 1.1 ± 0.6 | 0.09 |
 | Max post ICU | 1.0 ± 1.0 | 0.9 ± 0.8 | 0.33 |
   Diabetics | Preoperative | 1.0 ± 0.3 | 1.2 ± 1.1 | 0.11 |
 | Max in the ICU | 1.3 ± 1.2 | 1.4 ± 1.0 | 0.31 |
 | Max post ICU | 1.2 ± 1.7 | 1.3 ± 1.4 | 0.57 |
Morbidity, n (%): | Â | Â | Â | Â |
   Non-diabetics | Cardiac | 56 (24.0) | 62 (10.6) | < 0.0001 |
 | Renal | 9 (3.9) | 4 (0.7) | < 0.01 |
 | Pulmonary | 7 (3.0) | 38 (6.5) | 0.06 |
 | Infectious | 23 (9.9) | 25 (4.3) | < 0.01 |
 | Other | 9 (3.9) | 24 (4.1) | 1.0 |
   Diabetics | Cardiac | 22 (31.4) | 46 (28.4) | 0.64 |
 | Renal | 4 (5.7) | 5 (3.1) | 0.45 |
 | Pulmonary | 6 (8.6) | 15 (9.3) | 1.0 |
 | Infectious | 5 (7.1) | 7 (4.3) | 0.35 |
 | Other | 2 (2.9) | 8 (4.9) | 0.72 |
30-day Mortality, n (%): | Â | Â | Â | Â |
   Non-diabetics |  | 7 (3.0) | 5 (0.9) | < 0.05 |
   Diabetics |  | 4 (5.6) | 4 (2.5) | 0.25 |
Cause of death, n (%): | Â | Â | Â | Â |
   Cardiac |  | 4 (36.4) | 2 (22.2) | 0.64 |
   Respiratory |  | 0 (0.0) | 1 (11.1) | 0.45 |
   Sepsis |  | 1 (9.1) | 1 (11.1) | 1.0 |
   Multi organ failure |  | 5 (45.4) | 4 (44.4) | 1.0 |
   Other |  | 1 (9.1) | 1 (11.1) | 1.0 |