Skip to main content

Table 4 Perioperative data

From: Tight perioperative glucose control is associated with a reduction in renal impairment and renal failure in non-diabetic cardiac surgical patients

Group

Subgroup

Control

Insulin

p Value

Study interval

 

August to December 2004

June 2005 to June 2006

 

Procedure, n (%):

CABG

97 (31.8)

218 (29.3)

0.41

 

Valve

132 (43.3)

291 (39.0)

0.21

 

Combined

76 (24.9)

236 (31.7)

0.03

 

Redo

43 (14.2)

104 (13.9)

1.0

 

Emergency

33 (10.9)

61 (8.2)

0.19

ICU length of stay (days), median (min-max)

 

2 (1 to 73)

2 (1 to 106)

0.61

Aprotinin usage, n (%)

 

29 (9.5)

103 (13.8)

0.06

Administration of intravenous diuretics into the ICU, n(%)

 

50 (16.4)

121 (16.2)

1.0

Patients with packed cell transfusion, n (%)

 

240 (78.7)

524 (70.3)

0.006

Packed cells per patient, median (min-max)

 

2 (0 to 18)

2 (0 to 19)

0.66

Blood glucose level (mg/dL):

Induction

109 ± 39

104 ± 24

0.20

 

End of surgery

115 ± 25

108 ± 22

< 0.001

 

Admission to ICU

118 ± 29

107 ± 22

< 0.001

 

Mean in the ICU

133 ± 29

103 ± 15

< 0.0001

Serum creatinine levels (g/dL):

    

   Non-diabetics

Preoperative

1.0 ± 0.7

1.0 ± 0.5

0.99

 

Max in the ICU

1.3 ± 1.0

1.1 ± 0.6

0.09

 

Max post ICU

1.0 ± 1.0

0.9 ± 0.8

0.33

   Diabetics

Preoperative

1.0 ± 0.3

1.2 ± 1.1

0.11

 

Max in the ICU

1.3 ± 1.2

1.4 ± 1.0

0.31

 

Max post ICU

1.2 ± 1.7

1.3 ± 1.4

0.57

Morbidity, n (%):

    

   Non-diabetics

Cardiac

56 (24.0)

62 (10.6)

< 0.0001

 

Renal

9 (3.9)

4 (0.7)

< 0.01

 

Pulmonary

7 (3.0)

38 (6.5)

0.06

 

Infectious

23 (9.9)

25 (4.3)

< 0.01

 

Other

9 (3.9)

24 (4.1)

1.0

   Diabetics

Cardiac

22 (31.4)

46 (28.4)

0.64

 

Renal

4 (5.7)

5 (3.1)

0.45

 

Pulmonary

6 (8.6)

15 (9.3)

1.0

 

Infectious

5 (7.1)

7 (4.3)

0.35

 

Other

2 (2.9)

8 (4.9)

0.72

30-day Mortality, n (%):

    

   Non-diabetics

 

7 (3.0)

5 (0.9)

< 0.05

   Diabetics

 

4 (5.6)

4 (2.5)

0.25

Cause of death, n (%):

    

   Cardiac

 

4 (36.4)

2 (22.2)

0.64

   Respiratory

 

0 (0.0)

1 (11.1)

0.45

   Sepsis

 

1 (9.1)

1 (11.1)

1.0

   Multi organ failure

 

5 (45.4)

4 (44.4)

1.0

   Other

 

1 (9.1)

1 (11.1)

1.0

  1. Data are presented as mean ± SD or number (%) unless otherwise mentioned.
  2. CABG, coronary artery bypass graft; ICU, Intensive Care Unit; SD, standard deviation.