From: Metformin-associated lactic acidosis in an intensive care unit
Dialysis (n = 16) | No dialysis (n = 14) | P value | |
---|---|---|---|
Age (years) | 66.9 ± 11.6 | 66.6 ± 12.4 | 0.57 |
Sex ratio male/female | 7/9 | 7/7 | 0.61 |
SAPSII | 61 ± 12 | 43 ± 11 | 0.04 |
Charlson index | 3.5 ± 1.0 | 2.5 ± 0.7 | 0.12 |
Reason for ICU referral | |||
Shock (%) | 43.8 | 35.7 | 0.58 |
Acute renal failure (%) | 37.5 | 21.4 | 0.11 |
Suicide attempt (%) | 12.5 | 7.1 | 0.37 |
Other (%) | 6.3 | 35.8 | 0.01 |
Mechanical ventilation (%) | 43.8 | 28.6 | 0.16 |
Vasopressors (%) | 68.8 | 50 | 0.13 |
Acute renal failure (%) | 93.8 | 64.3 | 0.02 |
Arterial pH | 7.11 ± 0.20 | 7.26 ± 0.12 | 0.07 |
Arterial lactate (mmol/L) | 11.2 ± 4.8 | 8.4 ± 2.6 | 0.24 |
Arterial bicarbonate (mmol/L) | 9.8 ± 5.8 | 16.4 ± 3.2 | 0.006 |
Creatinine (mg/L) | 60.4 ± 38.0 | 27.6 ± 16.6 | 0.01 |
Length of stay in ICU (days) | 19.4 ± 8.2 | 5.3 ± 2.1 | 0.009 |
Mortality rate (%) | 31.3 | 28.6 | 0.82 |