Table 1 Patients' characteristics on admission according to their outcome.
From: Metformin-associated lactic acidosis in an intensive care unit
All patients (n = 30) | Survivors (n = 21) | Non-survivors (n = 9) | p value | |
|---|---|---|---|---|
Age (years) | 66.8 ± 13.6 | 66.1 ± 12.6 | 68.4 ± 11.4 | 0.90 |
Sex ratio male/female | 15/15 | 7/14 | 8/1 | 0.10 |
SAPSII | 60 ± 21 | 53 ± 12 | 75 ± 23 | 0.004 |
Charlson index | 3 ± 2 | 3 ± 1 | 3 ± 2 | 0.28 |
Reason for ICU referral | ||||
Shock (%) | 40.0 | 23.8 | 77.8 | 0.002 |
Acute renal failure (%) | 30.0 | 42.9 | 0 | 0.03 |
Suicide attempt (%) | 10.0 | 14.3 | 0 | 0.31 |
Other (%) | 20.0 | 19.0 | 22.2 | 0.86 |
Mechanical ventilation (%) | 36.7 | 33.3 | 55.6 | 0.68 |
Vasopressors (%) | 60 | 52.4 | 77.8 | 0.24 |
Acute renal failure (%) | 80 | 71.4 | 100 | 0.14 |
Arterial pH | 7.18 ± 0.19 | 7.19 ± 0.21 | 7.16 ± 0.10 | 0.15 |
Arterial lactate (mmol/L) | 9.9 ± 4.1 | 10.2 ± 4.3 | 9.2 ± 3.7 | 0.58 |
Arterial bicarbonate (mmol/L) | 13.2 ± 5.7 | 11.8 ± 6.1 | 16.3 ± 3.0 | 0.12 |
Creatinine (mg/L) | 45.0 ± 30.7 | 50.9 ± 38.6 | 31.5 ± 12.5 | 0.30 |
Prothrombin time (sec) | 19 ± 2 | 17 ± 2 | 21 ± 3 | 0.04 |
Length of stay in ICU (days) | 12.8 ± 17.7 | 8.1 ± 10.2 | 23.7 ± 22.8 | 0.35 |