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Table 3 Global oxygen transport variables and acid-base balance of study patients

From: Phenylephrine versus norepinephrine for initial hemodynamic support of patients with septic shock: a randomized, controlled trial

  Baseline 12 hours P value
Oxygen delivery index (ml/min/m2)    0.951
   Phenylephrine 500 ± 205 498 ± 177  
   Norepinephrine 499 ± 139 506 ± 140  
Oxygen consumption index (ml/min/m2)    0.568
   Phenylephrine 164 ± 48 150 ± 41  
   Norepinephrine 173 ± 53 161 ± 58  
Oxygen extraction ratio (%)    0.816
   Phenylephrine 34 ± 9 32 ± 8  
   Norepinephrine 36 ± 11 32 ± 10*  
Hemoglobin (g/dl)    0.699
   Phenylephrine 8.4 ± 0.9 8.4 ± 1.1  
   Norepinephrine 8.3 ± 0.7 8.4 ± 0.6  
pHa (-log10c(H+))    0.435
   Phenylephrine 7.37 ± 0.07 7.37 ± 0.08  
   Norepinephrine 7.35 ± 0.09 7.34 ± 0.08  
Arterial base excess (mmol/l)    0.228
   Phenylephrine -0.2 ± 5.8 0.2 ± 6.3  
   Norepinephrine -2.4 ± 6.6 -3.0 ± 6.4  
Arterial carbon dioxide partial pressure (mmHg)    0.346
   Phenylephrine 44 ± 10 44 ± 10  
   Norepinephrine 41 ± 6 41 ± 6  
Arterial oxygen partial pressure (mmHg)    0.963
   Phenylephrine 128 ± 36 119 ± 31  
   Norepinephrine 121 ± 24 120 ± 26  
Arterial oxygen saturation (%)    0.912
   Phenylephrine 98 ± 2 98 ± 2  
   Norepinephrine 98 ± 1 98 ± 2  
Mixed venous oxygen saturation (%)    0.431
   Phenylephrine 66 ± 9 67 ± 9  
   Norepinephrine 64 ± 11 67 ± 10  
PaO2/FiO2    0.971
   Phenylephrine 229 ± 103 208 ± 89  
   Norepinephrine 222 ± 75 218 ± 71  
  1. PaO2/FiO2, ratio of arterial oxygen partial pressure and inspiratory oxygen fraction (Horovitz index). *P < 0.05 versus baseline (significant time effect).