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Table 2 Outcome parameters for different severities of sepsis

From: The impact of the severity of sepsis on the risk of hypoglycaemia and glycaemic variability

Outcome parameters

Sepsis n = 47

Severe sepsis n = 83

Septic shock n = 61

p valuesa

Median SAPS II [14] (median/IQR)

38.1 (28.1 to 42.0)

38.0 (33.5 to 44.0)

45.8 (38.3 to 51.5)

< 0.0001 b

Median SOFA [15] (median/IQR)

6.0 (4.0 to 7.6)

5.5 (4.5 to 7.5)

8.9 (7.0 to 11.3)

< 0.0001 b

Acute renal failure, post-admission (n/%)

10 (21.3%)

37 (44.6%)

34 (55.7%)

0.0008 c

Patients with CRRT (n/%)

6 (12.8%)

12 (14.5%)

21 (35.0%)

0.0035 c

Duration of septic episodes (days; median/IQR)

2.0 (1.0 to 6.0)

4.0 (2.0 to 7.0)

10.0 (7.0 to 19.0)

<0.0001 b

Time of ventilation (hours; median/IQR)

37.3 (0.0 to 760.9)

61.0 (0.0 to 933.9)

308.1 (2.4 to 2052.9)

< 0.0001 c

Length of stay (hours; median/IQR)

166.5 (95.0 to 320.0)

213.0 (135.0 to 412.0)

391.0 (216.0 to 870.0)

< 0.0001 c

28 day mortality (n/%)

5 (10.6%)

7 (8.4%)

15 (24.6%)

0.0166 b

ICU mortality (n/%)

5 (10.6%)

9 (10.8%)

25 (41.0%)

< 0.0001 b

Hospital mortality (n/%)

7 (15.6%)

13 (16.5%)

26 (43.3%)

0.0003 b

  1. a Significance level p < 0.05; p values for the comparisons between the different sepsis groups were calculated using Kruskal–Wallis analysis of variance (b) and Chi-square test (c), as appropriate.
  2. CRRT = continuous renal replacement therapy; ICU = intensive care unit; IQR = Interquartile Range; SAPS II = Simplified Acute Physiology Score; SOFA = Sepsis-Related Organ Failure Assessment.