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Table 1 Intestinal mucosal damage grading score.

From: The adenosine deaminase inhibitor erythro-9-[2-hydroxyl-3-nonyl]-adenine decreases intestinal permeability and protects against experimental sepsis: a prospective, randomised laboratory investigation

Grade

Histological characteristics

Grade 0

Normal mucosal villi

Grade 1

Subepithelial Gruenhagen's space (oedema), usually at the apex of the villus

Grade 2

Extension of the subepithelial space with moderate lifting of epithelial layer from the lamina propria

Grade 3

Massive epithelial lifting down the sides of villi. A few tips may be denuded

Grade 4

Denuded villi with lamina propria and dilated capillaries exposed

Grade 5

Digestion and disintegration of lamina propria; haemorrhage and ulceration