Acute kidney injury is common, parallels organ dysfunction or failure, and carries appreciable mortality in patients with major burns: a prospective exploratory cohort study

Table 4 Early and late acute kidney injury: characteristics, multiple organ failure, and sepsis

	Early AKI (n = 17)	Late AKI (n = 14)	P value
Age, years	48.9 (39.7 to 58.1)	62.6 (49.7 to 75.5)	0.07
Total body surface area, percentage burned	53.3 (41.0 to 65.6)	39.8 (26.4 to 53.2)	0.13
Full thickness burns, percentage	39.4 (28.1 to 50.7)	23.0 (12.2 to 33.8)	0.04
Multiple organ failure	14	10	0.47
Sepsis	15	12	0.83
Lowest value of MAP for days 1–3, mm Hg	57.5 (54.9 to 60.2)	59.1 (54.3 to 63.9)	0.53
Plasma myoglobin for days 1–2, μg/L	1,167 (-484 to 2,820)	220 (103 to 337)	0.24
Mechanical ventilation	17	13	-
Length of stay, days	45.7 (27.8 to 63.6)	60.6 (27.9 to 93.4)	0.37

Data are mean (95% confidence interval) or number of patients. Early acute kidney injury (AKI) is defined as when creatinine reached the level for Risk within the first 7 days; late AKI occurred between days 8 and 60. Multiple organ failure is defined as 3 to 4 score points in two or more organ dimensions of the sequential organ failure assessment score. (Contingency table, Pearson chi-square test for categorical variables, and Student t test for continuous data.) MAP, mean arterial pressure.

ISSN: 1364-8535