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Table 2 Processed EEG parameters at 2 minutes before the event, separated by patients with light versus deep sedation

From: Entropy and bispectral index for assessment of sedation, analgesia and the effects of unpleasant stimuli in critically ill patients: an observational study

  RE SE BIS P values
All events
   RSS score 1 to 4 (n = 539) 79 (35 to 97) 61 (30 to 86) 66 (48 to 89) All P < 0.001 (Mann-Whitney)
   RSS score > 4 (n = 160) 34 (26 to 58) 31 (24 to 48) 41 (34 to 58)  
Sedation boli
   RSS score 1 to 4 (n = 192) 85 (39 to 97) 73 (34 to 86) 67 (49 to 91) All P < 0.001 (Mann-Whitney)
   RSS score > 4 (n = 60) 33 (26 to 48) 31 (33 to 51) 40 (33 to 51)  
Opiate boli
   RSS score 1 to 4 (n = 179) 56 (30 to 96) 43 (26 to 85) 59 (46 to 83) All P < 0.001 (Mann-Whitney)
   RSS score > 4 (n = 60) 31 (23 to 41) 29 (31 to 44) 40 (31 to 44)  
ETS
   RSS score 1 to 4 (n = 168) 89 (45 to 97) 75 (36 to 86) 74 (50 to 91) RE: P = 0.012
   RSS score > 4 (n = 40) 50 (30 to 92) 44 (27 to 80) 60 (44 to 80) SE: P = 0.018
BIS: P = 0.058
  1. RSS score 1 to 4 indicates light sedation, and RSS score > 4 indicates deep sedation. Values are expressed as median (interquartile range). BIS, bispectral index; EEG, electroencephalogram; ETS, endotracheal suctioning; RE, response entropy; RSS, Ramsay Sedation Scale; SE, state entropy.