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Table 2 Processed EEG parameters at 2 minutes before the event, separated by patients with light versus deep sedation

From: Entropy and bispectral index for assessment of sedation, analgesia and the effects of unpleasant stimuli in critically ill patients: an observational study

 

RE

SE

BIS

P values

All events

   RSS score 1 to 4 (n = 539)

79 (35 to 97)

61 (30 to 86)

66 (48 to 89)

All P < 0.001 (Mann-Whitney)

   RSS score > 4 (n = 160)

34 (26 to 58)

31 (24 to 48)

41 (34 to 58)

 

Sedation boli

   RSS score 1 to 4 (n = 192)

85 (39 to 97)

73 (34 to 86)

67 (49 to 91)

All P < 0.001 (Mann-Whitney)

   RSS score > 4 (n = 60)

33 (26 to 48)

31 (33 to 51)

40 (33 to 51)

 

Opiate boli

   RSS score 1 to 4 (n = 179)

56 (30 to 96)

43 (26 to 85)

59 (46 to 83)

All P < 0.001 (Mann-Whitney)

   RSS score > 4 (n = 60)

31 (23 to 41)

29 (31 to 44)

40 (31 to 44)

 

ETS

   RSS score 1 to 4 (n = 168)

89 (45 to 97)

75 (36 to 86)

74 (50 to 91)

RE: P = 0.012

   RSS score > 4 (n = 40)

50 (30 to 92)

44 (27 to 80)

60 (44 to 80)

SE: P = 0.018

BIS: P = 0.058

  1. RSS score 1 to 4 indicates light sedation, and RSS score > 4 indicates deep sedation. Values are expressed as median (interquartile range). BIS, bispectral index; EEG, electroencephalogram; ETS, endotracheal suctioning; RE, response entropy; RSS, Ramsay Sedation Scale; SE, state entropy.