Table 3 Pooled summary results of the prognostic value of elevated brain natriuretic peptide in acute pulmonary embolism
From: Prognostic value of brain natriuretic peptide in acute pulmonary embolism
Endpoints | OR (95% CI) | Sensitivity (95% CI) | Specificity (95% CI) | LR+ (95% CI) | LR- (95% CI) | PPV (95% CI) | NPV (95% CI) |
|---|---|---|---|---|---|---|---|
Short-term death (12 studies, 868 patients) | 6.57 (3.11–13.91) | 0.93 (0.85–0.98) | 0.48 (0.44–0.51) | 1.64 (1.39–1.94) | 0.34 (0.19–0.61) | 0.14 (0.11–0.18) | 0.99 (0.97–1.00) |
Death resulting from PE (10 studies, 684 patients) | 6.10 (2.58–14.25) | 0.92 (0.81–0.98) | 0.52 (0.48–0.56) | 1.76 (1.33–2.34) | 0.37 (0.19–0.71) | 0.13 (0.10–0.17) | 0.99 (0.97–1.00) |
Serious adverse events (9 studies, 688 patients) | 7.47 (4.2–13.15) | 0.89 (0.83–0.93) | 0.48 (0.44–0.52) | 1.70 (1.44–2.01) | 0.28 (0.17–0.48) | 0.33 (0.29–0.38) | 0.94 (0.90–0.96) |