Table 2 Time evolution of systemic hemodynamics and regional blood flows

Cardiac index (ml/minute per kg)

Control

6

99 (72–112)

104 (79–172)

71 (55–103)

72 (51–167)

88 (82–232)

117 (110–232)

0.002

NE

7

107 (84–132)

96 (72–150)

70 (57–195)

103 (52–157)

100 (88–190)

161 (147–340)^b

0.001

Heart rate (beats/min)

Control

6

122 (84–134)

120 (102–200)

126 (98–171)

124 (95–187)

122 (94–176)

128 (96–176)

0.7

NE

7

105 (89–139)

122 (92–174)

120 (102–197)

123 (103–171)

157 (113–185)

202 (170–223)^b

0.006

SVI (cardiac index/heart rate)

Control

6

0.77 (0.6–1.3)

0.88 (0.7–0.9)

0.57 (0.4–0.7)

0.58 (0.4–0.8)

0.81 (0.6–1.3)

0.94 (0.8–1.3)

0.003

NE

7

0.95 (0.8–1.3)

0.86 (0.5–1.1)

0.66 (0.5–1)

0.86 (0.4–0.9)

0.81 (0.6–1.1)

0.76 (0.7–1.7)

0.045

MPAP (mmHg)

Control

6

12.5 (11–14)

25.5 (16–34)

29.5 (24–42)

29 (22–37)

30.5 (19–36)

25.5 (21–36)

0.018

NE

7

12 (9–18)

29 (18–41)

30 (24–38)

24 (21–36)

30 (19–56)

25 (19–49)

0.003

PCWP (mmHg)

Control

6

2 (1–3)

6 (4–6)

5 (4–8)

4 (3–6)

5 (3–12)

3 (3–5)

0.016

NE

7

3 (0–7)

7 (3–11)

6 (4–9)

5 (4–7)

6 (4–9)

5 (2–7)

0.004

Oxygenation index (mmHg/%)

Control

6

475 (445–512)

432 (354–496)

380 (316–507)

372 (313–413)

369 (272–410)

349 (326–398)

0.002

NE

7

488 (407–548)

420 (367–445)

388 (294–453)

382 (317–496)

353 (195–478)

325 (222–390)

0.001

Hepatic artery flow (ml/minute per kg)

Control

5

3.7 (1.7–11.5)

2.6 (2–7.6)

1.1 (0.3–1.9)

2.1 (0.5–2.9)

4.5 (0.6–5.5)

3.5 (1.7–5.8)

0.037

NE

7

3.9 (0.5–7.9)

1.4 (0.9–6.5)

1.3 (0.1–2.7)

1.2 (0.2–7.2)

2.8 (0.6–7.3)

3 (0.3–8.9)

0.002

Portal vein flow (ml/minute per kg)

Control

6

20 (16–22)

16.9 (12–23)

11.5 (6–14)

11.9 (9–16)

16.2 (10–32)

18.6 (13–32)

<0.001

NE

7

19.6 (12–26)

13.8 (10–20)

11.6 (8–16)

14 (10–22)

15.8 (12–27)

19.1 (12–31)

0.001