Table 3 Comparison of outcome between daily interruption of sedation and sedation algorithm
| Â | Daily interruption of sedation n = 36 | Sedation algorithm n = 38 | P value | ||
|---|---|---|---|---|---|
| Â | Median | 95% CI | Median | 95% CI | Â |
Total duration of mechanical ventilation, days | 6.7 | 4.1, 10.4 | 3.9 | 2.9, 4.9 | 0.0003 |
Intensive care unit length of stay, days | 15 | 9.1, 21.2 | 8 | 6.5, 8.7 | < 0.0001 |
Hospital length of stay, days | 23 | 14.8, 28.7 | 12 | 11.3, 16.0 | 0.01 |
| Â | Median | IQR | Median | IQR | Â |
28-day ventilator-free survival | 16.1 | 0.00, 21.77 | 23.1 | 19.16, 25.06 | 0.004 |
Midazolam equivalents, mg/kg-day | 0.2 | 0.01, 1.48 | 0.4 | 0.01, 1.32 | 0.70 |
Fentanyl equivalents, μg/kg-day | 0.5 | 0.09, 2.43 | 1.2 | 0.12, 2.44 | 0.36 |
Propofol, μg/kg-day | 0 | 0.0, 5817.0 | 0 | 0.0, 6589.0 | 0.39 |