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Table 2 Survival rates of neonatal ECMO

From: Extracorporeal membrane oxygenation for severe acute respiratory failure

    

Control group

ECMO group

 

Reference

Year

Study design

Patients total (n)

n

survival rate (%)

n

survival rate (%)

P

[80]

1985

RCT 'play the winner'*

12

1

0

11

100

Not reported

[82]

1989

RCT (phase 1+2)

39

10

60

29

97

<0.05

[81]

1993

RCT

41

19

89

22

91

NS

[83]

1996

RCT

185

92

41

93

68

<0.001

[84]

1999

Uncontrolled study

100

-

-

100

82

-

  1. *Bartlett et al [80] used a special randomized play-the-winner statistical method; the chance of randomly assigning an infant to one treatment or the other is influenced by the outcome of treatment of each patient in the study. If one treatment is more successful, more patients are randomly assigned to that treatment.