Table 2 Diagnostic performance of the eosinophil count and the C-reactive protein level in the prediction of sepsis on intensive care unit admission
From: Eosinopenia is a reliable marker of sepsis on admission to medical intensive care units
Variable | Noninfection versus infection | SIRS versus infection | ||
|---|---|---|---|---|
| Â | C-reactive protein level | Eosinophil cell count | C-reactive protein level | Eosinophil cell count |
Cutoff value | >70 mg/l | <50 cells/mm3 | >80 mg/l | <40 cells/mm3 |
Sensitivity (%) | 68 (59 to 76) | 80 (71 to 86) | 68 (59 to 79) | 80 (71 to 86) |
Specificity (%) | 61 (47 to 74) | 91 (79 to 96) | 55 (32 to 76) | 80 (55 to 93) |
Positive likelihood ratio | 1.77 (1.25 to 2.51) | 9.12 (3.9 to 21) | 1.52 (0.92 to 2.50) | 4.00 (1.65 to 9.65) |
Negative likelihood ratio | 0.52 (0.39 to 0.69) | 0.21 (0.15 to 0.31) | 0.57 (0.41 to 0.81) | 0.25 (0.17 to 0.36) |
Area under the receiver operating characteristic curve | 0.77 (0.70 to 0.84) | 0.89 (0.83 to 0.94) | 0.77 (0.67 to 0.87) | 0.84 (0.74 to 0.94) |