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Table 2 Diagnostic performance of the eosinophil count and the C-reactive protein level in the prediction of sepsis on intensive care unit admission

From: Eosinopenia is a reliable marker of sepsis on admission to medical intensive care units

Variable Noninfection versus infection SIRS versus infection
  C-reactive protein level Eosinophil cell count C-reactive protein level Eosinophil cell count
Cutoff value >70 mg/l <50 cells/mm3 >80 mg/l <40 cells/mm3
Sensitivity (%) 68 (59 to 76) 80 (71 to 86) 68 (59 to 79) 80 (71 to 86)
Specificity (%) 61 (47 to 74) 91 (79 to 96) 55 (32 to 76) 80 (55 to 93)
Positive likelihood ratio 1.77 (1.25 to 2.51) 9.12 (3.9 to 21) 1.52 (0.92 to 2.50) 4.00 (1.65 to 9.65)
Negative likelihood ratio 0.52 (0.39 to 0.69) 0.21 (0.15 to 0.31) 0.57 (0.41 to 0.81) 0.25 (0.17 to 0.36)
Area under the receiver operating characteristic curve 0.77 (0.70 to 0.84) 0.89 (0.83 to 0.94) 0.77 (0.67 to 0.87) 0.84 (0.74 to 0.94)
  1. Data in parentheses are 95% confidence intervals. Noninfection, negative + systemic inflammatory response syndrome (SIRS); infection, sepsis + severe sepsis + septic shock.