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Figure 1 | Critical Care

Figure 1

From: Pharmacodynamic optimization of β-lactams in the patient care setting

Figure 1

In vivo potency as a pharmacodynamic parameter for antibiotic therapy. Maintaining antibiotic concentrations above the minimum inhibitory concentration (MIC) is necessary to achieve in vivo potency and is dependent on the pharmacokinetics of the drug. AUC, area under the concentration-time curve; Cmax, maximum plasma concentration; T > MIC, time spent above the MIC.

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