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Table 5 Cardiac medications

From: Detecting myocardial infarction in critical illness using screening troponin measurements and ECG recordings

  MI, N (%) (N = 37) Elevated cTn, N (%) (N = 15) No cTn elevation, N (%) (N = 51) p value1 p value2
Antiplatelet agents 26 (70.3) 7 (46.7) 16 (31.4) 0.001 - MI vs cTn, p = 0.126
- cTn vs no cTn elevation, p = 0.358
- MI vs no cTn elevation, p < 0.0001
Anticoagulant UFH 7 (19.4) 0 (0) 0 (0) 0.001 - MI vs cTn, p = 0.090
- cTn vs no cTn elevation, p = NE
- MI vs no cTn elevation, p = 0.001
Anticoagulant LMWH 3 (8.3) 0 (0) 0 (0) 0.064 - MI vs cTn, p = 0.546
- cTn vs no cTn elevation, p = NE
- MI vs no cTn elevation, p = 0.072
Anticoagulant Warfarin 8 (22.2) 3 (20.0) 4 (8.0) 0.156 - MI vs cTn, p = 1.000
- cTn vs no cTn elevation, p = 0.338
- MI vs no cTn elevation, p = 0.112
Long acting nitrates 19 (51.4) 5 (33.3) 6 (12.0) <0.0001 - MI vs cTn, p = 0.358
- cTn vs no cTn elevation, p = 0.109
- MI vs no cTn elevation, p < 0.0001
Statin 19 (51.4) 7 (46.7) 18 (35.3) 0.306 - MI vs cTn, p = 1.000
- cTn vs no cTn elevation, p = 0.547
- MI vs no cTn elevation, p = 0.189
ACE inhibitors/ARBs 11 (29.7) 5 (33.3) 7 (14.0) 0.123 - MI vs cTn, p = 1.000
- cTn vs no cTn elevation, p = 0.128
- MI vs no cTn elevation, p = 0.108
Beta-blockers 25 (67.6) 5 (33.3) 20 (39.2) 0.014 - MI vs cTn, p = 0.032
- cTn vs no cTn elevation, p = 0.769
- MI vs no cTn elevation, p = 0.010
Calcium channel blocker 13 (35.1) 4 (26.7) 11 (21.6) 0.369 - MI vs cTn, p = 0.747
- cTn vs no cTn elevation, p = 0.731
- MI vs no cTn elevation, p = 0.225
Diuretic 25 (67.6) 9 (60.0) 17 (33.3) 0.004 - MI vs cTn, p = 0.749
- cTn vs no cTn elevation, p = 0.078
- MI vs no cTn elevation, p = 0.002
Digoxin 8 (22.2) 0 (0) 2 (3.9) 0.007 - MI vs cTn, p = 0.087
- cTn vs no cTn elevation, p = 0.594
- MI vs no cTn elevation, p = 0.014
  1. ARBs = angiotensin receptor blockers; cTn = cardiac troponin; IV = intravenous; LMWH = low molecular weight heparin; MI = myocardial infarction; NE = not estimable; 1p value indicates a three-way comparison;2p value indicates a two-way comparison.