Mask intolerance due to pain, discomfort or claustrophobia |
Inability to improve gas exchanges and/or dyspnea |
Haemodynamic instability or evidence of cardiac ischaemia or |
ventricular dysarrhythmia |
Need for urgent endotracheal intubation to manage secretions or |
protect the airways |
Inability to improve mental status, within 30 min after the application of |
noninvasive positive pressure ventilation, in hypercapnic, lethargic |
chronic obstructive pulmonary disease patients or agitated hypoxaemic |
patients |