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Influence of first glycemia determination in acute coronary syndrome: long-term prognosis

Introduction

Hyperglycemia at the moment of hospitalization is associated with a worse prognosis in patients with acute coronary syndrome (ACS). We introduce a study about the influence of glycemic levels at hospital admission in patients with ACS.

Methods

We studied glycemic levels of 611 patients with ACS at hospitalized admission consecutively. We established three groups based on the glycemic levels results: Group 1, <114 mg/dl; Group 2, 114–163 mg/dl; Group 3, >163 mg/dl. The clinical and evolution characteristics were evaluated and we made a median of 3 years follow-up.

Results

Group 3 presented significantly older age, higher hypertension levels and more diabetes, peripheral arteriopathy and chronic renal failure cases. During the follow-up we found in Group 3 the worst Killip stage at the moment of hospitalization, a higher rate of heart failure (44%) and atrial fibrillation and a minor survival rate at the end of the pursuit (Group 1, 92%; Group 2, 89% and Group 3, 82%, P = 0.03).

Conclusion

High levels of glycemia at the first determination in ACS patients are a long-term prognostic factor. It is necessary to know the influence of glycemic levels for ACS prognosis when a correct control of the level is obtained during the ACS acute phase.

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Babarro, E.G., Acuna, J.G., Lago, A.L. et al. Influence of first glycemia determination in acute coronary syndrome: long-term prognosis. Crit Care 12, P149 (2008). https://doi.org/10.1186/cc6370

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Keywords

  • Atrial Fibrillation
  • Acute Coronary Syndrome
  • Hyperglycemia
  • Chronic Renal Failure
  • Evolution Characteristic