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Table 2 Regional blood flow and oxygen delivery during infusion of vasopressin

From: Vasopressin in septic shock: effects on pancreatic, renal, and hepatic blood flow

Time   300 minutes 360 minutes 480 minutes
Celiac trunk (mL/kg per minute)a,b     
  Group C 11 ± 3 12 ± 2 12 ± 2
  Group V 17 ± 6 23 ± 5c 23 ± 5c
  Group S 19 ± 8 17 ± 5 16 ± 4
  Group SV 25 ± 17 31 ± 18d 30 ± 17d
Liver flow (mL/kg per minute)a,b,e     
  Group C 36 ± 3 35 ± 5 33 ± 4
  Group V 38 ± 9 31 ± 6c 33 ± 5d
  Group S 45 ± 8 37 ± 6c 35 ± 5c
  Group SV 43 ± 7 29 ± 6c 31 ± 6d
DO2I PV (mL/kg per minute)a,b,e     
  Group C 2.7 ± 0.4 2.6 ± 0.5 2.6 ± 0.4
  Group V 2.5 ± 0.6 1.2 ± 0.2c 1.4 ± 0.2c
  Group S 2.7 ± 0.5 2.2 ± 0.5d 2.1 ± 0.4c
  Group SV 3.1 ± 0.7 1.3 ± 0.6c 1.7 ± 0.4c
DO2I HA (mL/kg per minute)a,b     
  Group C 0.3 ± 0.3 0.4 ± 0.3 0.4 ± 0.3
  Group V 0.5 ± 0.2 0.8 ± 0.3 0.8 ± 0.2
  Group S 0.6 ± 0.3 0.6 ± 0.3 0.6 ± 0.3
  Group SV 0.6 ± 0.3 1.0 ± 0.7c 1.0 ± 0.7c
DO2I liver (mL/kg per minute)a     
  Group C 3.2 ± 0.4 3 ± 0.6 3.1 ± 0.5
  Group V 3.0 ± 0.7 2.0 ± 0.5c 2.2 ± 0.3c
  Group S 3.3 ± 0.6 2.8 ± 0.6 2.7 ± 0.6d
  Group SV 3.6 ± 0.8 2.3 ± 0.9c 2.6 ± 0.9c
Renal artery (mL/kg per minute)a,b     
  Group C 8.7 ± 1.3 9.3 ± 1.3 9.1 ± 1.5
  Group V 8.9 ± 2.2 7.6 ± 2.3d 8.9 ± 2.7
  Group S 8.1 ± 3.0 8.8 ± 3.5 9.0 ± 4.0
  Group SV 6.2 ± 2.3 5.4 ± 1.6 7 ± 2.4
DO2I kidney (mL/kg per minute)a,e     
  Group C 1.1 ± 0.2 1.1 ± 0.3 1.2 ± 0.3
  Group V 1.0 ± 0.2 0.7 ± 0.2c 0.9 ± 0.3
  Group S 0.7 ± 0.4 0.8 ± 0.5 0.9 ± 0.6c
  Group SV 0.7 ± 0.2 0.6 ± 0.2 0.8 ± 0.3d
  1. A continuous infusion of vasopressin (0.06 IU/kg per hour) was started in groups V and SV at t = 300 minutes. Animals in groups C and S received intravenous saline only.
  2. ap < 0.01 time-group interaction groups V versus C: effect of vasopressin in control animals.
  3. bp < 0.01 time-group interaction groups SV versus S: effect of vasopressin in septic animals.
  4. cp < 0.01 compared to t = 300 minutes.
  5. dp < 0.05 compared to t = 300 minutes.
  6. ep < 0.05 Mann-Whitney test (area under curve): effect of vasopressin in non-septic versus septic animals.
  7. Celiac trunk: blood flow in the celiac trunk. DO2I HA: oxygen delivered by the hepatic artery. DO2I kidney: total oxygen delivered by the left renal artery. DO2I liver: total oxygen delivery to the liver. DO2I PV: oxygen delivered by the portal vein. Group C: non-septic control group. Group S: septic control group. Group SV: septic test group treated with vasopressin. Group V: non-septic vasopressin control group. Liver flow: total liver blood flow. Renal artery: blood flow in the left renal artery.