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Table 2 Baseline data from isolated heart and isolated papillary muscle preparations

From: Platelet-derived exosomes from septic shock patients induce myocardial dysfunction

 

Isolated heart

Isolated papillary muscle

Parameters

Heart rate (bpm)

+dP/dtmax (mm Hg/s)

-dP/dtmax (mm Hg/s)

DTmax (g)

Resting tension (g)

+dT/dt (g/s)

-dT/dt (g/s)

Septic exosomes

123 ± 4

3,676 ± 366

2,925 ± 336

5.3 ± 0.4

0.75 ± 0.07

52.6 ± 5.5

22 ± 3

Control exosomes

128 ± 3

3,136 ± 340

2,321 ± 469

5.7 ± 0.4

0.74 ± 0.1

63.8 ± 4.5

32.7 ± 2

P value

0.562

0.352

0.286

0.545

0.936

0.218

0.05

  1. Data for isolated heart preparations are from nine experiments for septic exosomes and five experiments for control exosomes; data for isolated papillary muscle preparations are from eight experiments for septic exosomes and four experiments for control exosomes. +dP/dtmax, maximal positive derivative of left ventricular pressure; -dP/dtmax, maximal negative derivative of left ventricular pressure; DTmax, maximal developed tension of isolated papillary muscle; +dT/dt, positive temporal derivative of developed tension; -dT/dt, negative temporal derivative of developed tension.
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Critical Care

ISSN: 1364-8535