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Table 2 Baseline data from isolated heart and isolated papillary muscle preparations

From: Platelet-derived exosomes from septic shock patients induce myocardial dysfunction

  Isolated heart Isolated papillary muscle
Parameters Heart rate (bpm) +dP/dtmax (mm Hg/s) -dP/dtmax (mm Hg/s) DTmax (g) Resting tension (g) +dT/dt (g/s) -dT/dt (g/s)
Septic exosomes 123 ± 4 3,676 ± 366 2,925 ± 336 5.3 ± 0.4 0.75 ± 0.07 52.6 ± 5.5 22 ± 3
Control exosomes 128 ± 3 3,136 ± 340 2,321 ± 469 5.7 ± 0.4 0.74 ± 0.1 63.8 ± 4.5 32.7 ± 2
P value 0.562 0.352 0.286 0.545 0.936 0.218 0.05
  1. Data for isolated heart preparations are from nine experiments for septic exosomes and five experiments for control exosomes; data for isolated papillary muscle preparations are from eight experiments for septic exosomes and four experiments for control exosomes. +dP/dtmax, maximal positive derivative of left ventricular pressure; -dP/dtmax, maximal negative derivative of left ventricular pressure; DTmax, maximal developed tension of isolated papillary muscle; +dT/dt, positive temporal derivative of developed tension; -dT/dt, negative temporal derivative of developed tension.