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Table 1 Clinical data for septic patients and healthy controls

From: Platelet-derived exosomes induce endothelial cell apoptosis through peroxynitrite generation: experimental evidence for a novel mechanism of septic vascular dysfunction

Characteristic

Patients (n = 12)

Controls (n = 10)

P

Age

58.3 ± 21

39.5 ± 13

0.02

Platelet count/ml

(187 ± 45) × 106

(270 ± 116) × 106

0.03

Exosome mg protein/sample

9.6 ± 3.9

10.6 ± 4.5

0.56

Infection

   

   Gram-negative

6

n.a.

 

   Gram-positive

2

n.a.

 

   Candida

1

n.a.

 

   Unidentified

3

n.a.

 

Site of origin

   

   Respiratory

7

n.a.

 

   Blood

2

n.a.

 

   Urinary

1

n.a.

 

   Peritonitis

1

n.a.

 

   Trauma

1

n.a.

 

Neutrophil count/ml

(12.1 ± 5.7) × 103

(5.6 ± 1.5) × 103

0.002

Dysfunction

   

   Shock

8

n.a

 

   Respiratory

8

n.a.

 

   Renal

3

n.a.

 

   Hepatic

1

n.a.

 
  1. n.a., not applicable.