Table 1 Factors for preharvesting serum creatinine level greater than 120 μmol/L
From: Impact of intensive care on renal function before graft harvest: results of a monocentric study
All patients (n = 143) | Preharvesting creatinine | ||
|---|---|---|---|
<120 μmol/L (n = 112) | >120 μmol/L (n = 31) | ||
Demographic data | |||
Women, number (percentage) | 54 (38) | 50 (45) | 4 (13)a |
Age (years) (mean ± SD) | 38 ± 14 | 38 ± 13 | 39 ± 15 |
Causes of ICU admission | |||
Head trauma, number (percentage) | 70 (49) | 50 (45) | 20 (65)a |
Intracranial bleeding, number (percentage) | 57 (40) | 53 (47) | 4 (13)a |
Cerebral anoxia, number (percentage) | 8 (5.5) | 4 (3.5) | 4 (13) |
Suicide, number (percentage) | 8 (5.5) | 5 (4.5) | 3 (10) |
ICU steps | |||
Duration of stay in ICU (hours) (mean ± SD) | 70 ± 64 | 76 ± 66 | 49 ± 48a |
Duration of brain death (hours) (mean ± SD) | 30 ± 14 | 29 ± 12 | 33 ± 18 |
Duration of brain death >24 hours (percentage) | 58 (41) | 50 (44) | 8 (26) |
Catecholamines | |||
Dopamine, number (percentage) | 37 (26) | 32 (29) | 5 (16) |
Dobutamine, number (percentage) | 11 (8) | 10 (9) | 1 (3) |
Epinephrine, number (percentage) | 51 (36) | 31 (28) | 20 (64)a |
Norepinephrine, number (percentage) | 101 (71) | 80 (71) | 21 (68) |
Fluid expansion | |||
Isotonic saline solution (mL) (mean ± SD) | 3,655 ± 4,003 | 3,667 ± 4,247 | 3,612 ± 3,015 |
Lactate ringer (mL) (mean ± SD) | 2,582 ± 2,598 | 2,665 ± 2,633 | 2,280 ± 2,483 |
Gelatin (mL) (mean ± SD) | 446 ± 928 | 466 ± 971 | 370 ± 763 |
Hydroxyethylstarch, number (percentage) | 113 (79) | 86 (77) | 27 (87) |
Hydroxyethylstarch (mL) (mean ± SD) | 1,170 ± 1,080 | 1,140 ± 1,100 | 1,274 ± 1,015 |
Osmotherapy | |||
Mannitol 20% (mL) (mean ± SD) | 185 ± 285 | 200 ± 301 | 132 ± 215 |
Hypertonic saline solution 7.5% (mL) (mean ± SD) | 131 ± 296 | 130 ± 281 | 130 ± 351 |
Urine output modulators | |||
Furosemide, number (percentage) | 36 (25) | 30 (27) | 6 (19) |
Furosemide (mg) (mean ± SD) | 16 ± 51 | 16 ± 56 | 12 ± 28 |
Desmopressin, number (percentage) | 114 (80) | 98 (87) | 16 (52)a |
Desmopressin (μg) (mean ± SD) | 5.9 ± 5.7 | 6.8 ± 6.1 | 2.7 ± 3a |
Hemodynamic profile during ICU resuscitation | |||
Cardiac arrest, number (percentage) | 26 (18) | 14 (12) | 12 (39)a |
Shock, number (percentage) | 93 (65) | 67 (60) | 26 (83)a |
Duration of shock (minutes) (mean ± SD) | 80 ± 142 | 61 ± 104 | 150 ± 223a |
MAP upon admission (mm Hg) (mean ± SD) | 89 ± 25 | 93 ± 23 | 75 ± 26a |
Preharvesting MAP (mm Hg) (mean ± SD) | 81 ± 17 | 82 ± 18 | 77 ± 16 |
Respiratory profile during ICU resuscitation | |||
Acute respiratory distress syndrome, number (percentage) | 53 (37) | 37 (33) | 16 (52) |
Acute lung injury, number (percentage) | 33 (23) | 30 (27) | 3 (10)a |
Characteristics of renal function | |||
Oliguria, number (percentage) | 66 (46) | 44 (39) | 22 (71)a |
Serum creatinine upon admission (μmol/L) (mean ± SD) | 89 ± 38 | 79 ± 26 | 125 ± 49a |
Preharvesting serum creatinine (μmol/L) (mean ± SD) | 98 ± 61 | 75 ± 21 | 180 ± 83a |
Acidosis (pH <7.30), number (percentage) | 45 (31) | 24 (21) | 21 (68)a |
Disseminated intravascular coagulation, number (percentage) | 24 (17) | 13 (12) | 11 (35)a |
Injection of contrast, number (percentage) | 97 (68) | 77 (69) | 20 (64) |