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Table 1 Pediatric modified pRIFLE criteria for AKI using changes in estimated creatinine clearance

From: Urine neutrophil gelatinase-associated lipocalin is an early marker of acute kidney injury in critically ill children: a prospective cohort study

pRIFLE stratum

Change in eCCl

Risk (R)

eCCl decrease by 25% from baseline renal function

Injury (I)

eCCl decrease by 50% from baseline renal function

Failure (F)

eCCl decrease by 75% from baseline renal function or eCCl < 35 ml/min per 1.73 m2

  1. The original pediatric Risk, Injury, Failure, Loss, End Stage Kidney Disease criteria [21] for acute kidney injury (AKI) also include pRIFLE L (loss) and pRIFLE E (end stage kidney disease), identifying those patients who require dialysis for periods longer than 30 days. eCCl, estimated creatinine clearance; pRIFLE, pediatric modified Risk, Injury, Failure, Loss, End Stage Kidney Disease.
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Critical Care

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