Table 1 Studies on hypothermia in malignant hemispheric infarction
From: Clinical review: Therapy for refractory intracranial hypertension in ischaemic stroke
Authors | Number | Target temperature | Time to induction of hypothermia (hours) | Duration of hypothermia (hours) |
|---|---|---|---|---|
Schwab et al., 1998 [95] | 25 | 33°C (external cooling) | 4–24, mean 14 ± 7 | 48–72 |
Schwab et al., 2001 [134] | 50 | 32°C–33°C (external cooling) | 4–75, mean 22 ± 9 | 24–72 |
Georgiadis et al., 2001 [99] | 6 | 33°C (endovascular cooling) | 12–58, mean 28 ± 17 | 48–78 |
Georgiadis et al., 2002 [124] | 19 | 33°C (n = 8 endovascular cooling; n = 11 external cooling) | 18–24, mean 24 | 24–116 |
Milhaud et al., 2005 [94] | 12 | 32°C–33°C (external cooling) | 4–24, mean 11 ± 7 | 120–504 |