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Table 1 Studies on hypothermia in malignant hemispheric infarction

From: Clinical review: Therapy for refractory intracranial hypertension in ischaemic stroke

Authors Number Target temperature Time to induction of hypothermia (hours) Duration of hypothermia (hours)
Schwab et al., 1998 [95] 25 33°C (external cooling) 4–24, mean 14 ± 7 48–72
Schwab et al., 2001 [134] 50 32°C–33°C (external cooling) 4–75, mean 22 ± 9 24–72
Georgiadis et al., 2001 [99] 6 33°C (endovascular cooling) 12–58, mean 28 ± 17 48–78
Georgiadis et al., 2002 [124] 19 33°C (n = 8 endovascular cooling; n = 11 external cooling) 18–24, mean 24 24–116
Milhaud et al., 2005 [94] 12 32°C–33°C (external cooling) 4–24, mean 11 ± 7 120–504