Gender, infection, critical illness, and death: superior survival for female trauma patients admitted to the intensive care unit treated for infection in a dedicated, prospective, multicenter study

Table 1 Logistic regression analysis assessing predictors of mortality in patients with ICU-acquired infections

	Infected trauma patients (n = 652)			Infected nontrauma patients (n = 397)
Variable	Odds ratio	95% confidence interval	P value	Odds ratio	95% confidence interval	P value
Female gender	0.45	0.22–0.95	0.036	1.15	0.696–1.911	0.58
Age, per year	1.02	0.10–1.04	0.087	1.04	1.019–1.062	<0.001
White race	1.00	-		1.00	-	-
Black race	0.62	0.24–1.62	0.33	1.08	0.44–2.59	0.87
Other race	1.03	0.29–3.67	0.97	3.61	1.08–12.1	0.037
Any comorbidity	0.89	0.40–2.00	0.77	0.76	0.29–1.98	0.57
Chronic corticosteroid use	0.48	0.05–5.0	0.54	1.35	0.66–2.74	0.41
Hepatic insufficiency	4.25	1.33–13.6	0.015	1.61	0.78–3.33	0.20
Cardiac disease	1.18	0.49–2.82	0.72
Baseline serum creatinine ≥2.0 (units)	7.46	1.11–50.1	0.039
Malignancy	0.17	0.018–1.56	0.12	1.39	0.80–2.44	0.24
Body mass index, per kg/m²				0.98	0.96–1.01	0.24
Admission from home				1.03	0.41–2.60	0.95
McCabe score at ICU admission, per point	1.21	0.60–2.44	0.59	1.35	0.91–2.01	0.14
APACHE II score at ICU admission, per point	1.07	1.02–1.12	0.0081	1.08	1.04–1.12	<0.001
WHO functional status at ICU admission, per point	1.46	0.89–2.39	0.14
Multiple Organ Dysfunction score at ICU admission, per point	1.12	1.04–1.22	0.0040
Probability of trauma survival	0.49	0.23–1.02	0.055
ICU length of stay, per day	1.02	0.97–1.07	0.42
Hospital length of stay, per day	0.95	0.91–0.98	0.032

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