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Table 4 Inflammatory markers in survivors and in fatal cases

From: A comparison of high-mobility group-box 1 protein, lipopolysaccharide-binding protein and procalcitonin in severe community-acquired infections and bacteraemia: a prospective study

Variable

Survivors (n = 138)

Fatal cases (n = 16)

P valuea

High-mobility group-box 1 protein (ng/ml)

4.9 (2.9–9.1)

5.6 (3.4–14.2)

NS

Lipopolysaccharide-binding protein (μg/ml)

70.7 (45.6–112.3)

70.6 (57.1–89.7)

NS

Procalcitonin (ng/ml)

1.3 (0.17–8.9)

1.7 (0.4–12.2)

NS

IL-6 (pg/ml)

66.5 (21.2–174.5)

193.5 (47.9–589)

NSb

C-reactive protein (mg/l)

185 (109–263)

198 (130.5–274)

NS

White blood cells (× 109/l)

13.2 (8.5–17.3)

14.7 (11.5–20.9)

NS

Neutrophils (× 109/l)

11.2 (6.8–15.5)

12.7 (8.7–18.9)

NS

  1. Data presented as median and interquartile range. NS, not significant. aWilcoxon's two sample test. bP = 0.06.