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Table 4 Univariate analysis of patients deceased at day 30 or admitted to ICU versus all others patients, and identification of variables associated with critical illness after stepwise logistic regression analysis

From: Serum procalcitonin measurement as diagnostic and prognostic marker in febrile adult patients presenting to the emergency department

  Univariate analysis   Multivariate analysis
  Group II (n = 166) Group I (n = 55) P Odds ratio
[95% CI]
P
Male sex 91 (54%) 33 (60%) NS   
Age (year) 55 ± 22 65 ± 16 0.001 1.02 [1.00–1.04] 0.013
Temperature (°C) 39.1 ± 0.6 39.4 ± 0.7 0.01   
Heart rate > 120 beats/min 33 (20%) 19 (34%) 0.03 2.36 [1.22–4.96] 0.02
Systolic blood pressure < 90 mmHg 1 (1%) 3 (5%) 0.047   
White blood cell count (/mm3) 10272 ± 7195 26601 ± 83080 0.01   
Previous antibiotic treatment 24 (14%) 7 (13%) NS   
Antibiotics initiated in ED 129 (79%) 47 (85%) NS   
Immunocompromised status 44 (26%) 24 (44%) 0.02   
Positive blood culture or thick smear (Plasmodium) 33 (20%) 18 (33%) NS   
Platelet count (103/mm3) 199 ± 93 194 ± 102 NS   
Haemoglobin level (mg/l) 12.8 ± 2 12 ± 2.8 0.02   
CRP (mg/l) 103 ± 112 149 ± 144 0.01   
Creatinine ≥ 120 μmol/l 29 (17%) 23 (42%) < 0.001 2.16 [1.04–4.49] 0.04
PCT μg/l 3.1 ± 10.8, 0.3 [0.3–0.5], (0–115) 24.3 ± 63.7, 1.9 [0.8–4.7], (0–316) < 0.001   
PCT ≥ 2 μg/L 36 (22%) 27 (49%) < 0.001 2.51 [1.25–5.04] 0.001
  1. Shown is a univariate analysis comparing group I (patients deceased at day 30 or admitted to intensive care unit [ICU]) and group II (all other patients) and identification of variables associated with critical illness (ICU admission or death) after stepwise logistic regression analysis. Data are expressed as number of patients (%), mean ± standard deviation, median [95% CI] (extrems). For multivariate analysis all other P values were NS. CI, confidence interval; CRP, C-reactive protein; ED, emergency department; NS, not significant; PCT, procalcitonin.