Table 4 Univariate analysis of patients deceased at day 30 or admitted to ICU versus all others patients, and identification of variables associated with critical illness after stepwise logistic regression analysis
Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|
Group II (n = 166) | Group I (n = 55) | P | Odds ratio [95% CI] | P | |
Male sex | 91 (54%) | 33 (60%) | NS | ||
Age (year) | 55 ± 22 | 65 ± 16 | 0.001 | 1.02 [1.00–1.04] | 0.013 |
Temperature (°C) | 39.1 ± 0.6 | 39.4 ± 0.7 | 0.01 | ||
Heart rate > 120 beats/min | 33 (20%) | 19 (34%) | 0.03 | 2.36 [1.22–4.96] | 0.02 |
Systolic blood pressure < 90 mmHg | 1 (1%) | 3 (5%) | 0.047 | ||
White blood cell count (/mm3) | 10272 ± 7195 | 26601 ± 83080 | 0.01 | ||
Previous antibiotic treatment | 24 (14%) | 7 (13%) | NS | ||
Antibiotics initiated in ED | 129 (79%) | 47 (85%) | NS | ||
Immunocompromised status | 44 (26%) | 24 (44%) | 0.02 | ||
Positive blood culture or thick smear (Plasmodium) | 33 (20%) | 18 (33%) | NS | ||
Platelet count (103/mm3) | 199 ± 93 | 194 ± 102 | NS | ||
Haemoglobin level (mg/l) | 12.8 ± 2 | 12 ± 2.8 | 0.02 | ||
CRP (mg/l) | 103 ± 112 | 149 ± 144 | 0.01 | ||
Creatinine ≥ 120 μmol/l | 29 (17%) | 23 (42%) | < 0.001 | 2.16 [1.04–4.49] | 0.04 |
PCT μg/l | 3.1 ± 10.8, 0.3 [0.3–0.5], (0–115) | 24.3 ± 63.7, 1.9 [0.8–4.7], (0–316) | < 0.001 | ||
PCT ≥ 2 μg/L | 36 (22%) | 27 (49%) | < 0.001 | 2.51 [1.25–5.04] | 0.001 |