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Table 2 Comparison of groups with creatinine clearance lower and higher than 80 ml/minute per 1.73 m2

From: Cystatin C and beta2-microglobulin: markers of glomerular filtration in critically ill children

 

CrC < 80 ml/minute per 1.73 m2

CrC > 80 ml/minute per 1.73 m2

P value

 

N

Mean (95% CI)

N

Mean (95% CI)

 

CrC

14

47.7 (40.6–54.8)

11

112.6 (85.0–140.3)

< 0.01

Schwartz

14

82.8 (64.6–100.9)

11

132.2 (111.7–152.7)

< 0.01

Serum Cr (mg/dl)

14

0.45 (0.36–0.54)

11

0.38 (0.29–0.47)

NS

Serum cystatin C (mg/l)

14

0.83 (0.67–0.99)

11

0.51 (0.38–0.64)

< 0.01

Serum B2M (mg/l)

14

2.60 (1.94–3.26)

11

1.50 (1.02–1.90)

< 0.05

  1. Creatinine clearance (CrC), creatinine clearance estimation by Schwartz formula (Schwartz), serum creatinine (Cr), serum cystatin C, and serum beta2-microglobulin (B2M) in patients with renal dysfunction (CrC less than 80 ml/minute per 1.73 m2) and normal renal function are shown. CI, confidence interval; N, number of patients; NS, not significant.