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Table 3 Prometheus in liver failure

From: Bench-to-bedside review: Current evidence for extracorporeal albumin dialysis systems in liver failure

    

Improvements

 

Study

Classification

Number

Controlled

Biochemical

CVS

CNS

Survival

Rifai et al. [28]

Acute on chronic liver failure

11

No

Yes

No

No

28% at 30 days

Skwarek et al. [31]

Acute liver failure

13

No

Yes

N/A

N/A

23% at 6 months

Laleman et al. [12]

Acute on chronic liver failure (ethanol)

18

Yes

Yesa

No

N/A

N/A

  1. Biochemical improvements: statistically significant reduction in bilirubin, bile acids, creatinine, and ammonia. aBilirubin and bile acids only. CNS, improvement in hemodynamic parameters (mean arterial pressure, heart rate, vasopressor requirements); CNS, decrease in hepatic encephalopathy grade (neurological improvement); N/A, not assessed.
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Critical Care

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