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Poster presentation | Open | Published:

Profile of patients admitted to the intensive care unit after exogenous intoxication at a university hospital

Introduction

Patients admitted to the ICU for exogenous intoxication are normally intoxicated with medicines such as benzodiazepines, and also chemical substances such as organophosphates, requiring rapid treatment.

Objective

To analyze patient profiles of those patients admitted to the ICU of HEG after exogenous intoxication between June 2005 and July 2006.

Materials and methods

All patients with previous diagnosis of exogenous intoxication who were admitted to the ICU of HEG were analyzed retrospectively. A protocol was developed, including age, gender, type of intoxication agent, APACHE II score, and ICU and hospital lengths of stay, need for orotracheal intubation and complications.

Results

There were 343 patients in total admitted to the ICU; 12 (2.76%) were because of exogenous intoxication. The average age was 34.6 years, and the hospital length of stay was 17.8 days. Most patients were men (seven patients or 58.3%). All required orotracheal intubation and the mean time of mechanical ventilation was 7.8 days. Organophosphate was the agent in 10 (83.3%) patients, which required atropine. There were complications in six (50%) patients: aspirative pneumonia (four patients or 33.3%) and reintubation (16.7%).

Conclusion

Most intoxications were caused by organophosphates. There were no deaths, which is different from the literature where the death rate ranges from 8% to 13%. In general, patients are young and treatment must be made quickly and efficiently to be successful.

References

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    Munidasa UDDB, Gawarammana IB, Kularathe SAM, et al.: Survival pattern in patients with with organophosphate poisoning receiving intensive care. J Toxicol 2004, 42: 343-347.

  2. 2.

    Tay SY, Tay DYH, Seow E, et al.: Patients admitted to an intensive care unit for poisoning. Ann Acad Med Singapore 1998, 27: 347-352.

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    Bosch TM, Van der Werf TS, Uges DRA, et al.: Antidepressant self-poisoning and ICU admissions in a University Hospital in the Netherlands. Pharm World Sci 2000, 22: 92-95. 10.1023/A:1008745130203

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Keywords

  • Intensive Care Unit
  • Pneumonia
  • Mechanical Ventilation
  • Emergency Medicine
  • Atropine