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Table 1

From: Early fluid replacement with hypertonic isoncotic solution guided by mixed venous oxygen saturation in experimental hypodynamic sepsis

 

T0

T30

T90

T120

T150

T270

MAP (mmHg)

      

   NS

102 ± 3.8

87 ± 5.4*

54 ± 7.3*

73 ± 9.5*

65 ± 10.2*

69 ± 15.7*

   HH

105 ± 5.2

87 ± 7.8*

54 ± 7.3*

63 ± 8.1*

66 ± 9.3*

56 ± 9.4*

CO (l/min)

      

   NS

2.1 ± 0.2

1.7 ± 0.1*

1.2 ± 0.2*,a,b

2.3 ± 0.3*

1.6 ± 0.2*,d

1.2 ± 0.2*

   HH

2.2 ± 0.1

1.5 ± 0.1*

1.1 ± 0.1*,a,b

1.5 ± 0.2*

1.5 ± 0.2*

0.8 ± 0.1*

PVBF (ml/min)

      

   NS

510 ± 91

324 ± 60

160 ± 44*,a

396 ± 85

275 ± 72*

167± 53*

   HH

561 ± 32

287 ± 31*

218 ± 39*

233 ± 47*

204 ± 29*

129 ± 29*

SpO2 (%)

      

   NS

92 ± 1.2

86 ± 3.5

74 ± 4.6*

87 ± 3.2

79 ± 4.3

65 ± 6.9*

   HH

89 ± 1.8

81 ± 3.9

68 ± 2.4*

70 ± 4.2

70 ± 3.6d

52 ± 6.9*

  1. P < 0.05 for the following comparisons: *vs baseline, aT90 vs T120, cT90 vs T270, cT120 vs T150, dT150 vs T270.
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