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Table 1 Case mix, outcome and activity for patients admitted to ICUs requiring chronic renal dialysis as compared with other patients

From: Case mix, outcome and activity for patients admitted to intensive care units requiring chronic renal dialysis: a secondary analysis of the ICNARC Case Mix Programme Database

 

Parameter

Patients requiring chronic renal dialysis

(n = 3,420)

Patients not requiring chronic renal dialysis

(n = 267,552)

P value

Case mix

Age (mean [SD]; years)

57.3

(15.8)

59.5

(19.6)

< 0.001

 

Male sex (n [%])

2,058

(60.2)

154,780

(57.9)

0.006

 

CPR before admission (n [%])

466

(13.6)

19,535

(7.3)

< 0.001

 

Mechanically ventilated (n [%])

2,107

(61.8)

167,840

(63.1)

0.135

 

Highest serum creatinine (mean [SD]; mg per 100 ml/mmol per l])

6.5

(3.2)/575 (283)

1.5

(1.3)/133 (115)

< 0.001

 

Lowest serum albumin (mean [SD]; g/l)

22.9

(7.7)

23.4

(8.5)

0.001

 

Lowest haematocrit (%)/haemoglobin (g/dl) (mean [SD])

26.9

(5.9)/9.0 (2.0)

31.3

(6.6)/10.4 (2.2)

< 0.001

 

APACHE II APS scorea (mean [SD])

17.2

(6.5)

12.6

(6.7)

<0.001

 

APACHE II scorea (mean [SD])

24.7

(7.0)

16.6

(7.3)

< 0.001

 

Surgical status (n [%])

    

< 0.001

 

   Nonsurgical

2,282

(66.7)

150,350

(56.2)

 
 

   Elective surgery

592

(17.3)

66,017

(24.7)

 
 

   Emergency surgery

545

(16.0)

50,947

(19.1)

 
 

Number of nonrenal organ system failuresb (n [%])

    

< 0.001

 

   None

1,156

(33.8)

107,140

(40.0)

 
 

   1

1,223

(35.8)

99,299

(37.1)

 
 

   2

743

(21.7)

46,447

(17.4)

 
 

   3+

298

(8.7)

14,666

(5.5)

 

Outcome

Mortality in ICU (n [%])

898

(26.3)

55,547

(20.8)

< 0.001

 

Ultimate hospital mortality (n [%])

1,379

(45.3)

77,869

(31.2)

< 0.001

Activity

ICU LOS (median [IQR]; days)

     
 

   Survivors

1.9

(0.9–4.2)

1.8

(0.9–4.5)

0.507

 

   Nonsurvivors

2.0

(0.6–6.0)

1.9

(0.7–6.1)

0.843

 

Total hospital LOS (median [IQR]; days)

     
 

   Survivors

25

(13–49)

17

(9–33)

< 0.001

 

   Nonsurvivors

15.5

(5–35)

8

(2–21)

< 0.001

 

Transfers from another ICU (n [%])

120

(3.5)

10,508

(3.9)

0.210

 

Readmissions within hospital stay (n [%])

306

(9.0)

12,676

(4.7)

< 0.001

 

Treatment withdrawn (n [%])

364

(10.7)

26,119

(9.8)

0.087

 

Destination following discharge (n [%])

    

< 0.001

 

   Ward, same hospital

1,788

(70.9)

155,487

(73.4)

 
 

   Recovery, same hospital

14

(0.6)

975

(0.5)

 
 

   ICU, same hospital

9

(0.4)

1,580

(0.8)

 
 

   HDU, same hospital

295

(11.7)

28,695

(13.6)

 
 

   Other intermediate care, same hospital

156

(6.2)

4,573

(2.2)

 
 

   ICU, other hospital

94

(3.7)

10,898

(5.2)

 
 

   HDU, other hospital

16

(0.6)

850

(0.4)

 
 

   Other hospital, not ICU/HDU

137

(5.4)

6,088

(2.9)

 
 

   Normal residence

12

(0.5)

2,662

(1.3)

 
  1. aAcute Physiology and Chronic Health Evaluation (APACHE) II exclusions: age < 16 years; intensive care unit (ICU) stay < 8 hours; readmissions within same hospital stay; transfers from another ICU; admissions following coronary artery bypass grafting; and admissions for primary burns. bOrgan system failures assessed physiologically according to the method of Knaus and coworkers [10]. APS, Acute Physiology Score; CPR, cardiopulmonary resuscitation; HDU, high dependency unit; IQR, interquartile range; LOS, length of stay; SD, standard deviation.