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Figure 3 | Critical Care

Figure 3

From: Glutamine induces heat-shock protein and protects against Escherichia coli lipopolysaccharide-induced vascular hyporeactivity in rats

Figure 3

Effects of alanyl-glutamine on heat-shock protein 70 (HSP70) expression in heart, aorta, lung, and liver in endotoxin rats. HSP70 expressions were analyzed by Western blotting analysis. Relative density refers to the ratio of HSP70 to GAPDH. The expression of HSP70 was significantly increased after lipopolysaccharide (LPS) injection compared with the control group in heart (a), aorta (b), lung (c), and liver (d) tissue. (*P < 0.05; n = 5). The expressions of HSP70 were much higher than those in the LPS shock group from four tissues in the Ala-Gln+LPS group (#P < 0.05; n = 5). Ala-Gln+LPS, alanyl-glutamine dipeptide + lipopolysaccharide shock; Ala+LPS, alanyl-glutamine dipeptide + lipopolysaccharide shock; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; LPS+Gln, alanyl-glutamine dipeptide + lipopolysaccharide shock.

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