| | LVHP-S | HVLP-S | HVLP-P | OA | NIR | C |
|---|
| | n = 10 | n = 10 | n = 10 | n = 10 | n = 4 | n = 5 |
|---|
| | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) |
|---|
logpcIII nondependent | 0.1564 (0.0971)a | 0.136 (0.1009)a | -0.1657 (0.0826) | -0.552 (0.1042) | -- | -0.3314 (0.1345) |
logpcIII dependent | 0.0978 (0.0744) | 0.0045 (0.085)a | -0.1309 (0.0636) | -0.1047 (0.0852) | -- | -0.4067 (0.0812) |
- Results are expressed as mean and standard deviation (SD). Post hoc analysis: (1) significant differences found within groups in nondependent versus dependent regions: aHVLP-S, p = 0.004; LVHP-S nondependent versus HVLP-S dependent, p = 0.0007; (2) significant differences found between groups: (i) HVLP-P versus HVLP-S, HVLP-P versus LVHP-S, and HVLP-P versus C, p < 0.001; (ii) HVLP-S versus OA and HVLP-S versus C, p < 0.001; (iii) LVHP-S versus OA and LVHP-S versus C, p < 0.001; (iv) OA versus C, p < 0.001. C, control group; HVLP-P, high volume-low positive end-expiratory pressure, prone; HVLP-S, high volume-low positive end-expiratory pressure, supine; logpcIII: logarithmic transformation of the expression of PC III mRNA normalized by GAPDH mRNA; LVHP-S, low volume-high positive end-expiratory pressure, supine; NIR, no injury, recruited; OA, oleic acid injury, no ventilation.
